Comparing Study Of Echocardiography And Cardioangiography On Measurement Of Patent Ductus Arteriosus

Objective:To measure the sizes of patent ductus arteriosus (PDA) by echocardiography (ECG), compare the results with those by cardioangiography (CAG)/X-ray angiography(XA), to analysis the correlation of measurements between ECG and XA, to explore the value of ECG on screening the size of PDA suitable for transcatheter occlusion.Methods:The study included141participants (37men and104women, average age5.60±6.67years old). The sizes of PDA including the length of PDA(PDAL), the aortic side diameter (PDADao) and the pulmonary side diameter (PDADpa) of PDA were measured from the parasternal great artery short-axis view (PSSA)and the suprasternal descending aorta long-axis view (SSLA) of ECG and left lateral projection of X-ray angiography (XA), and the other parameters such as the left ventricle end-diastolic diameter (LVEDD), the main pulmonary artery diameter (MPAD), the pressure drop of PDA shunt (AP) and the pulmonary artery systolic pressure (PASP) were measured by ECG. The sizes of PDA from PSSA, SSLA and XA were compared, and the correlations of the sizes of PDA between ECG and XA, the correlations between the other parameters by ECG and the PDADpa index by XA(PDADIpa-XA) and PSSA (PDADIpa-PSSA) were analyzed.Results:1. The difference of the sizes of PDA:(1) PDAL:both PSSA and SSLA were lower than XA (both P<0.05), and PSSA lower than SSLA (P<0.05);(2) PDADao: PSSA was lower than SSLA and XA (both P<0.05), but no significant difference between SSLA and XA (P>0.05);(3) PDADpa:both PSSA and SSLA were higher than XA (both P<0.05); and the PSSA lower than SSLA.2. Correlation:(1) correlation of the sizes of PDA:both PSSA and SSLA had positive correlations with XA (all P<0.01). And among these parameters, PDAL by SSLA, PDADao by SSLA and PDADpa by PSSA had better correlations with XA (r=0.92,0.87and0.91, respectively, all P<0.01);(2) correlations between the other parameters by ECG and the size of PDA:both LVEDD and MPA calibrated by body surface area (BSA) had positive correlations with PDADIpa-XA and PDADIpa-PSSA (all P<0.01), but the formers were lower than the latters; PASP calibrated by BSA had positive correlations with the PDADIpa-XA and PDADIpa-PSSA (both P<0.01), but the former was higher than the latters; and PASP had a negative correlation with△P (r=-0.79, P<0.01).Conclusions:1. There was difference between the sizes of PDA at different echocardiographic views, PDADpa by PSSA and the PDAL and the PDADao by the SSLA were more close to those parameters by XA.2. XA as a golden standard in measuring the size of PDA also had some limitations probably, ECG might be better in measuring the PDAL and PDADpa than XA or equal to it.3. Multiplane views of ECG can evaluate all the more accurately the size of PDA and play an important role in guiding transcatheter occlusion of PDA.