A Preliminary Study On Chemical Compositions Of Motan Resin From Motan Wax Of Yunnan Esan

Large amount of montan resin is generated as by-product during production of refined motan resin from motan wax and can not recycle. In order to ecological utilization, twenty-four comppunds were isolated from the montan resin by modern chemical separation methods, and the structures of twenty comppunds were elucidated by spectroscopic methods. They are Friedenlan-3-one (1),3-Epifriedlinol (2),3-hydroxy-oleanane (3),31-Homohopanoic acid (4),29-Homohopanoic acid (5), Bacteriohopanetetrol (6), Stigmastanol (7), Stigmasterol (8), bis-(7-methyl-nonane) phthalate (9), bis-(-methyl-hexane) phthalate (10),1.3-propane ester ethyl (11), dacane cyclohexane (12), methyl palmitate (13), methyl dodecyl (14), Methyl heptyal (15), tettadecane (16), hendecane (17), decane (18), octane (19), heptane (20). Those twenty compounds were isolated from montan resin for the first time,In addition, the pharmacological activities of YUNNAN ESAN motan resin made a preliminary exploratory research. YUNNAN ESAN motan resin on the effects of mouse models of xylene induced ear edema. The results found:montan wax from montan wax compound sample P-B, P-C, P-D, A-I, A-II group all has anti-inflammatory activity. Moreover, The study on the angiogenesis activity of YUNNAN ESAN montan wax:The activity of the extract of montan resin and the compounds isolated from it were tested with the chicken chorioallantoic membrane (CAM) neovascularisation model. The results showed that three fractions (P-D, A-Ⅰ, A-Ⅱ group) exhibited proangiogenic activity.