Effect Of Pulmonary Rehabilitation On Quality Of Life In Lung Cancer Postoperative Patients After Chemotherapy

Objectiveuse of pulmonary rehabilitation during chemotherapy in patients with lung cancer, and explore the effect of pulmonary rehabilitation on quality of life, negative emotion and self-efficacy in lung cancer postoperative patients during chemotherapy.MethodFrom July,2012to June,2013,100postoperative lung cancer patients needed chemotherapy were enrolled form the Department of lung cancer, Cancer Hospital of Tianjin Medical University. The patients were randomly divided into control group (50) and intervention group (50). Patients in the control group were treated with regular nursing care. Besides the regular nursing care, patients in the intervention group were given3month’s pulmonary rehabilitation. The quality of life, the negative emotion (anxiety and depression) and self-management efficacy were investigated at four different time, i.e. Enrolled, before the first, the second and the third chemotherapy to test the effect of pulmonary rehabilitation intervention. The survey instruments concluded cancer patients quality of life questionnaire (EORTC QLQ-C30), self-rating anxiety scale (SAS), self-rating depression scale (SDS). strategies used by people to promote health (SUPPH). The data were analyzed by SPSS16.0. Descriptive statistics, t test, χ2test,repeated measures analysis of variance etc were used to test the differences.Result1There were no significant differences between intervention group and control group in the general demographic information (such as age, sex, educational level, marital status, working conditions,medical conditions, family income,smoking index etc) and clinical data (operation type, pathology, pathological stage, chemotherapy etc)(P>0.05).2the quality of life:①At baseline, there no statistical significance (P>0.05) in the quality of life between two groups.②After the intervention, the scores of the physical function, role function, cognitive function and overall quality of life in the intervention group significantly higher than those in the control group (P<0.05); the scores of fatigue, nausea and vomiting, dyspnea, insomnia and appetite loss in the intervention group patients were significantly lower than those in the control group (P <0.05).③the scores of functional dimension, the scores of symptoms and the scores of overall quality of life are interacted between the factors and intervention time (P <0.05), the interactive contour map displays with the change of time, the scores of the functional dimension and the scores of overall quality of life were significantly higher, while, the scores of symptoms was significantly lower than the control group.3the negative emotion:①At baseline, there no statistical significance (P>0.05) in the negative emotion between two groups.②After the intervention, the scores of the self-rating anxiety scale (SAS) and self-rating depression scale (SDS) in the intervention group significantly lower than those in the control group (P<0.05).③the scores of the self-rating anxiety scale (SAS) and self-rating depression scale (SDS) are interacted between the factors and intervention time (P<0.05), the interactive contour map displays with the change of time, the scores of the self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were significantly lower than the control group.4self-efficacy sense:①At baseline, there no statistical significance (P>0.05) in the self-efficacy sense between two groups.②After the intervention, the scores of the self-efficacy sense in the intervention group significantly higher than those in the control group (P<0.05).③the scores of the self-efficacy sense are interacted between the factors and intervention time (P<0.05), the interactive contour map displays with the change of time. the scores of the self-efficacy sense was significantly higher than the control group.Conclusions1Pulmonary rehabilitation intervention can help lung cancer postoperative patients needed chemotherapy improve their quality of life2Pulmonary rehabilitation intervention can help lung cancer postoperative patients needed chemotherapy reduce their anxiety and depression3Pulmonary rehabilitation intervention can help lung cancer postoperative patients needed chemotherapy improve their self-efficacy.4It is still in the primary stage for the application of pulmonary rehabilitation and further researches needs to be done in the future.