Research On The Long-lasting Antibacterial Ability Of Silicon Rubber In Vitro And Its Effect On Mechanical Capacity By Adding Three Kinds Of Nanometer-sized Antibacterial Agents

[Objectives1To compare the antibacterial capability against Candida albicans and Staphylococcus aureus in vitro by adding three kinds of nanometer-sized silicon rubber with different mass fraction; to compare the long-lasting antibacterial ability against Candida albicans and Staphylococcus aureus in vitro by adding three kinds of nanometer-sized silicon rubber with same mass fraction; to compare the effects on mechanical property towards silicon rubber by adding three kinds of nanometer-sized silicon rubber with different mass fraction.[Materials and Methods] The first part:adding nano TiO2, nano ZnO and Ag-TiCh with the mass fraction of1.0%,2.0%,3.0%,4.0%and5.0%into silicon rubber to prepare antibacterial silicon rubber, respectively. To detect the antibacterial ability against Candida albicans and Staphylococcus aureus by film mulching method. The second part: adding the three antibacterial agents of mass fraction of4.0%into silicon rubber and conducted accelerated aging process, respectively, to test the antibacterial capability of silicon rubber of new prepared group and aging process group by dipping culture method. The third part:adding nano TiO2, nano ZnO and Ag-TiO2with the mass fraction of1.0%,2.0%,3.0%,4.0%and5.0%into silicon rubber and prepared antibacterial silicon rubber, examined its tensile strength, tear strength, elongation at break and shore hardness, analyzed the minimum effects on mechanical property of adding what kind of mass fraction by compared with the blank control group.[Results] The first part:there reflected inhibition function on Candida albicans and Staphylococcus aureus by adding three kinds of nanometer-sized inorganic antibacterial agent of silicon rubber, the antibacterial rate raised with the increase of mass fraction when added among1.0%-4.0%, the antibacterial rate decreased with the decrease of mass fraction when added5.0%. The second part:the antibacterial rate decreased with different level against Candida albicans and Staphylococcus aureus after conducting two kinds of accelerated aging process by adding three kinds of silicon rubber with the mass fraction of4.0%when compared to new prepared group. The third part:tensile strength and elongation at break of silicon rubber in nano ZnO group and nano TiOi group raised first and then decreased, Ag-TiO2group decreased gradually by adding among1.0%-5.0%. Tear strength of silicon rubber increased first and then decreased by adding three kinds of antibacterial agents with different mass fraction, the strength raised gradually.[Conclusions]1. The antibacterial capability was:Ag-TiO2>nano TiO2>nano ZnO by adding the same mass fraction; the antibacterial effect was optimum when added the mass fraction of4.0%by adding three kinds of silicon rubber.2. Silicon rubber reflected long-lasting antibacterial ability by adding nano ZnO and nano TiO2with mass fraction of4.0%.3. The optimal additive amount was3.0%for nano ZnO and nano TiO:and2.0%forAg-TiO2.