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Clinical Research Of The Prevention Of Severe Intrauterine Adhesion Separation Recurrence

Posted on:2015-10-17Degree:MasterType:Thesis
Country:ChinaCandidate:S LiFull Text:PDF
GTID:2284330431967929Subject:Obstetrics and gynecology
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Purpose: Intrauterine adhesions (intrauterine adhesion, IUA), also known asasherman syndrome which is caused by scar tissue developing in the process of ofuterus repairing.Uterine wall sticking together, destroy the normal structure of theuterus, causing less menstrual quantity, amenorrhea, dysmenorrhea, infertility orrecurrent abortion and other serious consequences. Hysteroscopic surgery developmentis getting better and better.It has the advantage of quick recovery, small trauma, lesscomplications.But the recurrence rate is high.We need to find more efficient way toprevent the recurrence of intrauterine adhesions.This research will compare with thetraditional method with comprehensive treatment method,by analysising the recurrencerate, menstrual recovery rate and pregnancy rate.Methods: There is a retrospective analysis of58patients from xingtai people’shospital.The patients were divided into group A during September2012-March2013.The patients were divided into group B during April2013to October2013.Thecomparing of two group’s average age and the degree of adhesion is Statisticallyinsignificant(p>0.05).Group A’s patients put IUD in the utrus, and take the medicine ofestrogen and progesterone after the operation.Different from Group A,group B’spatients use Balloon Foley Catheter and chitosan before using IUD.Back to review in1,3,9months after surgery.Results:(1)1month after the surgery: group A’s intrauterine adhesions recurrencerate is51.7%, the efficiency of menstrual recovery is55.2%; Group B’s intrauterineadhesions recurrence rate is31.0%, the efficiency of menstrual recovery is75.9%, Group B’s intrauterine adhesions recurrence rate is lower than group A (P <0.05), theefficiency of menstrual recovery is higher than group A (P <0.05), the comparingbetween the two groups have statistical significance;(2)3months after the surgery: group A’s intrauterine adhesions recurrence rate is34.5%, the efficiency of menstrual recovery is65.5%; Group B’s intrauterine adhesionsrecurrence rate is17.2%, the efficiency of menstrual recovery is82.8%, Group B’sintrauterine adhesions recurrence rate is lower than group A (P <0.05), the efficiency ofmenstrual recovery is higher than group A (P <0.05), the comparing between the twogroups have statistical significance;(3)9months after surgery: group A’s intrauterine adhesions recurrence rate is24.1%, he efficiency of menstrual recovery is75.9%, the pregnancy rate is29.4%;Group B’s intrauterine adhesions recurrence rate is10.3%, the efficiency of menstrualrecovery is89.7%, the pregnancy rate is55.6%, Group B’s intrauterine adhesionsrecurrence rate is lower than group A (P <0.05), the efficiency of menstrual recoveryand the pregnancy rate both are higher than group A (P <0.05), the comparing betweenthe two groups have statistical significance;Conclusion: By using the balloon catheter, chitosan, intrauterine device, estrogenand progesterone after the operation,the treatment of patients is better.
Keywords/Search Tags:intrauterine adhesions, Chitosan, prevention
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