The Relationship Between RRTI And MP And Other Risk Factors In Children

Objective: To investigate the role of mycoplasma pneumonia(MP) in recurrentrespiratory tract infections(RRTI) in children and set out comprehensive diagnosis andtreatment scheme for RRTI in children. Investigation of RRTI children may risk factorsat the same time,provide theoretical basis for prevention and control of children withRRTI susceptible of reasonable,improve the quality of life in children.Methods: In light of diagnosis criteria of RRTI,80children were selected asexperiment group at random,meanwhile80children with acute respiratory tractinfections as control group,from all children who see a doctor in the first hospitalaffiliated to Dalian medical university from January,2013to January2014.Gelatinparticle agglutination method(PA) and Cold agglutination test were used to test specificantibody IgM and IgG in venous blood at different time.Then we analyze the morbidityof MP in experiment group and control group,the difference of morbidity among sex,age and different risk factors.Meanwhile we collect other factors,such as birth, nutrientcondition,passive smoking and inaccurate use of antibiotics.In the end we statisticallyanalyze the risk factors of RRTI according to clinical results and medical history.Results：There are46males (57.5%) and34females (42.5%) in the trial group,whose average age is (3.76±2.18); meanwhile38males (47.5%) and42females (52.5%)in the control group, average age is (4.14±2.46).there is no statistical difference in sexand age (P>0.05), which means there is a comparability between the trail group and thecontrol group.1. According to statistical analysis, there is an obvious difference in the morbidityof MP between the two groups, the morbidity in trial group is38.75%, the control group is17.50%.2. There is a marked relationship between the morbidity of MP and a differentbetween sex in two groups (P＜0.05),moreover, the morbidity of MP in trial group ishigher than that in control group,no matter the gender is in male or female. But nodefinite relationships were proved between the sex and MP.3. Comparision of incidence of MP among different age stage between the twogroup: according to statistical analysis,there is no difference in morbidity of MP at ageof1~2and6~14. And there is an obvious difference at age of3~5(χ2=4.919,P=0.027).4. According to the disease characteristic, positive rate of MP in upper respiratoryinfection, bronchitis, pneumonia, asthma concurrent infection, capillary bronchitisrespectively is12.5%,22.58%,27.03%,31.82%,20.83%. Among those diseases, positiverate in upper respiratory infection is the lowest（12.5%）,asthma concurrent infection isthe highest（31.82%）.5. Comparision of other risk factors in relationship with RRTI between trial groupand control group: premature infant(χ2=11.181,P=0.001), nutrient deficient(χ2=5.478，P=0.019),lead paint (χ2=4.812,P=0.028),passive smoking(χ2=6.404,P=0.011), inaccurateuse of antibiotics(χ2=4.514,P=0.034), collective children (χ2=5.730,P=0.017).All thestatistical results reveal that those risk factors have marked relationship with RRTI.Conclusion：1. MP is one of the primary pathogens of RRTI.2. The rate of MP infection to collective children is higher.3. The morbidity of MP is obviously increased accompany with lower respiratoryinfection, of which asthma with pulmonary infection is the highest.4. Polyfactors such like premature infant, nutrient deficient, lead paint passivesmoking,inaccurate use of antibiotics and collective life are the risk factors of RRTI.