| ObjectiveChronic kidney disease (CKD) has caused extensive worldwide concern,and it has become an important public health problem because of its increasingincidence, poor prognosis, low awareness and high medical cost. According tothe recent reports, the total prevalence rate of our country is10.8%. So far, thereis no relevant epidemiological investigation of CKD in Shandong province. Thispaper intends to explore the epidemiological characteristics about CKD of adulthealth examination population in Tai’an city, and investigate the prevalence ofCKD and associated risk factors, learn the high risk group, which lay thefoundation for further health education and investigation of the CKD inprovince. Also aimed to improve the low knowledge status of this disease,change low awareness-rate status, raise the residents’ understanding of chronickidney disease, raise the attention of people, achieve the goal of early found andearly intervention.MethodsThis study adopted stratified cluster random sampling system method,based on health examination project in Tai’an city. Separately on the basis of theTai’an city population distribution, randomly select2Third-grade Class-Ahospitals and2Second-grade hospitals. Then randomly selected40units inTai’shan district and Dai’yue district from September to December of2012inthis four hospitals’ health physical examination centers. And then randomlyselected50residents (18full years old and more than18years old, residencetime for6months or more) as the research objects from each unit. There were320sampling units in this study, a total of16000people conducted questionnaire survey. Questionnaire included general situation, history ofdiseases associated with chronic kidney disease and family history, physicalheight, weight, and blood and urine specimen test, which reflecting the renalinjury and related risk factors. The integrated information number was14399.About repeated examination we only recorded the first check results. This studyobtained each respondents agreement, and all people signed a written informedconsent.ResultsA total of14399subjects with the complete information were entered thestatistical analysis. There were8561male residents, accounting for59.46%;5838female residents, accounting for40.54%. Male to female ratio was1.47:1.Average age was(48.97±17.02), minimum age was18and maximum age was89.Men was (49.64±16.65), female was (49.64±18.01), suggesting the agedifference was statistically significant between men and women（P=0.001,P<0.05）.In these residents, patients with hematuria was605. The total prevalencewas4.2%, male2.30%, female6.9%. Female prevalence was significantlyhigher than male, suggesting that hematuria was statistically significantdifference between the genders（P=0.000,P<0.05）.There was756cases of proteinuria in patients with positive, albuminuriamorbidity rates was5.25%. The prevalence of male was6.23%and theprevalence of women was3.82%. Men was higher than women, the prevalenceof proteinuria was statistically significant difference between different genders（P=0.000,P<0.05）.In the residents of this study, there was273people’s eGFR was less than60ml·min-1·(1.73m2)-1, which was calculated by the MDRD formula, eGFRdecreased prevalence was1.89; eGFR decline in prevalence between differentgender difference was statistically significant(P=0.002,P<0.05). eGFRdecreased obviously after60years of age, gradually decrease with the increaseof age.According to the criteria for the diagnosis of chronic kidney disease (CKD),the crowd with a total of1366patients with chronic kidney disease (CKD) in theMDRD formula, the prevalence rate of9.49%. Men was9.21%and women was9.85%. There was no statistically significant difference between the sexes(P=0.126,P>0.05). Prevalence of chronic kidney disease (CKD) graduallyincrease with the increase of age(P=0.000,P<0.05), the ratio was increasedobviously after60years of age.The cooperation of age and blood biochemical between CKD populationand non-CKD population. About age, body mass index, systolic blood pressure,diastolic blood pressure, serum creatinine, fasting blood glucose, triglyceride,total cholesterol, low density lipoprotein cholesterol, the former were higherthan the latter; And about eGFR, chronic kidney disease (CKD) was less than thenon-CKD population groups.ConclusionIn Tai’an city, the medical adult population prevalence of chronic kidneydisease (CKD) was9.49%,which showed that the prevalence of healthcheck-up crowd was higher, it should cause our highly attention. Witting ratewas1.4%and it was low. It is necessary to vigorously promote, improveresidents’ understanding of chronic kidney disease (CKD). Chronic kidneydisease (CKD) associated risk factors include increasing age was10years old,gender and high systolic blood pressure, history of kidney disease, diabetes,high blood triglycerides, high cholesterol, high uric acid hematic disease,smoking, this research was similar to those of developed countries and big citiesin China. |
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