| Objective:To investigate the prevalence of chronic kidney disease (CKD) and risk factors in the adult population in Tianshan district of UrumqiMethods:2131 residents from 4 communities in Tianshan district of Urumqi city were randomly selected by using a stratified, multistage sampling. All residents were interviewed and tested for morning spot urine of albumin to creatinine ratio (ACR) (abnormal:≥30 mg/g); morning spot urine dipstick of hematuria (abnormal:> 3 red blood cells/Hp or greater) and pyuria (abnormal:> 5 White blood cells/Hp) confirmed by urine microscopy; Reduced renal function-estimated glomerular filtration rate (e GFR) by abbreviated MDRD equation eGFR[abnormal:< 60 ml-min-1?(1.73 m2)-1]. The associations of kidney damage indicators with age, gender, hypertension, diabetsmellitus, smoking, income, education, cholesterol, triglyceride and smoking were detected by questionnaire and physical examination.Results:Eligible data of 2131 subjects were collected in the study.. After the adjustment of age and gender componen, the prevalence of albuminuria was detected in 2.63%(95%CI:1.78%-3.48%) of subjects, hematuria in 7.43%(95%CI:6.11%-8.75%) and reduced renal function in 1.72%(95%CI:1.08%-2.35%). Approximately 9.99% (95%CI:8.47%-11.55%) subjects had at least one indicator of kidney damage. Multivariate logistic regression display:Albuminuria, hematuria, age and hyperuricemia were independently associated with reduced renal function. Hematuria and reduced renal function were independently associated with albuminuria. Albuminuria, reduced renal function and female were independently associated with hematuria.Conclusions:The prevalence of chronic kidney disease is 9.99%and the recognition rate is 2.44%in urban adult population in western china. The risk factors of CKD in adult population in Urumqi city are similar with the metropolis in China and the developed countries. Population-based studies evaluating the prevalence of kidney damage in different communities have been limited in developing countries. We conducted a population-based screening study in Uygur people of Urumqi that aimed to identify the prevalence and associated risk factors of chronic kidney disease (CKD) in Uygur populations.Methods. We interviewed 2576 residents (>18 years) from four districts of Urumqi from June 2007 to January 2009 and tested for haematuria, albuminuria and reduced renal function. Associations between age, gender, smoking, diabetes mellitus, hypertension, hyperuricaemia and kidney damage were examined.Results. There were 2576 subjects enrolled in this study. After standardization for age, the prevalence of albuminuria, haematuria and reduced estimated glomerular filtration rate (eGFR) was3.58%,2.26%and 1.03%, respectively. Approximately 5.65%of the sample population had at least one indicator of kidney damage. Age, diabetes mellitus, hypercholesteremia, hyperuricaemia and hyperlipidaemia were independently associated with CKD.Conclusions, In the general uygur adult population from Urumqi,5.65%has either proteinuria, haematuria and/or reduced eGFR, indicating the presence of kidney damage, with an awareness of only 1.05%. The high prevalence and low awareness of CKD in this population suggest an urgent need for CKD prevention programmes in Uygur people. Objective:To set up the community intervention model for chronic kidney disease (CKD) and evalute the effect of the model.Methods:The CKD patients and non-CKD participants were divided into invention group and control group randomly based on the database of CKD which was established according to the epidemiological study. The comprehensive intervention was conducted on the all participants for one year, then the effect of intervention was evaluated.Results:After the comprehensive intervention, the awareness rate of chronic kidney disease in non-CKD participants increased by 48.7%, while the CKD patients increased by 33.48%; The percence of smoking in non-CKD participants decreased by 18.04%, while the CKD patients decreased by 30.02%; The recognition rate of rish factors and complication of CKD, compliance with dietary and pharmologic therapy were increased significantly, and the differences showed statistically significant (P<0.05); After comprehensive intervention, both of the systolic blood pressure and the diastolic blood pressure were decreased significantly (P<0.05).Conclusions:The community intervention is an effective measure for the prevention and control of chronic kidney disease.
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