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Elderly And Minors Hypertrophic Obstructive Cardiomyopathy Patients Underwent Ablation Compare The Efficacy And Safety

Posted on:2015-05-21Degree:MasterType:Thesis
Country:ChinaCandidate:H SuFull Text:PDF
GTID:2284330431964958Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
Objective Hypertrophic obstructive cardiomyopathy (H ypertrophic Cardiomyopathy, HOCM) is a more special hypertrophic cardiomyopathy, dueto asymmetric septal hypertrophy and left ventricular outflow tract(leftventriculeoutflow tract, LVOT) obstruction named. Percutaneoustransluminal septal myocardial ablation (P ercutaneoustransluminalseptalmyocardialabl ation PTSMA) interventional cardiology treatmentHOCM is a new hot spot. It does not need surgery, you can make the spacingportion ischemic necrosis of myocardial hypertrophy, outflow tractobstruction may relieve and improve cardiac function, reduce symptoms,improve exercise tolerance. This paper summarizes60years of age or olderhypertrophic obstructive cardiomyopathy patients treated with18rowsPTSMA PTSMA minors under the age of patients with recent-line treatment(≤30days), and security differences.Methods HOCM patients for over60years old in July1998-June2013implementing PTSMA therapy and clinical data and results of chemicalanalysis and intraoperative ablation age of18HOCM patients, the incidence of postoperative complications, discuss difference in efficacy in patientsaged60or older HOCM line PTSMA and safety of HOCM patients with minors.HOCM patients aged measurement data is normally distributed, with±s,between the two groups were compared using t test; minor HOCM patientsmeasured data for non-normally distributed data, the overall distributionof the two data sets is also a non-normal distribution, metering data aremedian (quartiles) to describe the groups were compared using thenon-parametric Wilcoxon test, count data were compared with χ2test orF isher ’s exact test, using SPSS13.0package, P <0.05is a significantResults PTSMA accepted HOCM treated patients, aged60or older44patients, of which43patients received PTSMA treatment, and after restingleft ventricular outflow tract premature pressure gradient lower thanbefore (14.98±16.26vs71.09±40.84, P=0.00039.60±20.25vs124.05±41.88, P=0.000).8patients underwent minor PTSMA treatment, leftventricular outflow tract pressure gradient was also significantly reduced(22.0vs63.5, P=0.017;37.5vs87.5, P=0.018). Old age group with a minorgroup between the two groups before and after surgery and after prematureresting left ventricular outflow tract pressure gradient was no significantdifference in the change (54.0vs38.5, P=0.288;80.0vs55.0, P=0.158)groups the total complication rate was not significantly different (50.0%vs37.5%p=0.790) compared to older women, but with a minor group in HOCMpatients over70years old, serious complications (including death, Ⅲdegree atrioventricular block, acute left heart failure) showed a greaterincidence trends.Conclusion Aged60or older HOCM patients as a minor line PTSMA HOCMpatients as safe and effective. However, women over the age of70PTSMAhigher likelihood of serious complications, caution should be implemented.
Keywords/Search Tags:Cardiomyopathy, hypertrophic obstructive, percutaneoustransluminal septal myocardial ablation
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