Preventive Application Of Budesonide Aerosol Inhalation Of Thyroid Benign Neoplasm Resection Patients After General Anesthesia Throat Complications Of The Clinical Curative Effect Observation

ObjectiveObserve anesthesia in patients with thyroid surgery in preventing atomizedinhalation budesonide after throat symptoms improve the situation.After evaluatingdifferent ways of atomization inhalation in patients with tracheal intubation throatsymptoms and signs of curative effect.Methods120cases of general anesthesia downlink endotracheal intubation surgicalresection of thyroid benign patients were randomly divided into four groups，eachgroup of30only：group A：N=30, budesonide1mg preoperative1hour, budesonide1mg postoperative8,24and48h for atomization inhalation；group B：N=30,budesonide1mg postoperative8,24and48h take atomization inhalation；group C：N=30，Postoperative period shall be5mg dexamethasone and10ml saline foraerosol inhalation；group D：N=30，Postoperative period shall be10ml saline foraerosol inhalation。Patient to sitting or semi supine position, all with oxygen as thedriving force atomization inhalation, atomizer vertical to the ground, atomizationtime for5min。 Observation each group patients postoperative throat situation,evaluating different ways for after atomized inhalation of patients with tracheaintubation throat symptoms and signs of curative effect。Results 1. Each group general information and take tube time comparison. Groups ofpatients age, smoking history and endotracheal intubation tube time comparison,there were no statistically significant difference (P>0.05)。2.Each group of symptoms and signs scores more。①：Pharynx pain VAS score:postoperative8,24and48h, group A pharynx pain VAS score less than group B，group B pharynx pain VAS score less than group C，group C pharynx pain VASscore is less than the control group，compared between two groups, pharynx painVAS score A <B <C <D, the difference had statistical significance (P <0.05).②：Cough VAS score: group A postoperative8,24and48h, cough VAS score lessthan group B, statistically significant difference (P <0.05);And each time there wasno statistically significant difference compared with group A group C (P>0.05),group D there was no statistically significant difference compared with group C (P>0.05), group D there was no statistically significant difference compared with groupA(P>0.05)；postoperative8h and48h, group C cough VAS score less than group B,difference was statistically significant (P <0.05); postoperative8h and24h, group Dcough VAS score less than group B, the difference was statistically significant (P <0.05); postoperative24h, there was no statistically significant difference comparedgroup C with group B (P>0.05); postoperative48h, there was no statisticallysignificant difference compared group D with group B (P>0.05).③. Voice hoarseVAS score: postoperative8,24and48h，Voice hoarse VAS score in group A wereless than group B、C group and the control group, the difference was statisticallysignificant (P <0.05)；Postoperative24and48h，voice hoarse VAS score in group Band C group were less than D group,the difference was statistically significant (P <0.05);Postoperative48h, Voice hoarse VAS group B were score less than group C,the difference was statistically significant (P <0.05);Postoperative8h and24h, therewas no statistically significant difference compared group C with group B (P>0.05); Postoperative8h, there was no statistically significant difference compared group Dwith group B (P>0.05); there was no statistically significant difference comparedgroup D with group C (P>0.05).3.The throat mucosa reaction classification comparisonThroat mucosa reaction classification result A <B <C <D. Mucosa reactionclassification in group A and B group were lower than that of C group and thecontrol group, group A and group C, group A and group D, group B and group D hadsignificant difference compared (P <0.05); Group A is slightly lower than group B,but there was no significant difference compared the two groups (P>0.05), group Ccompared with group B, group C and group D compare differences had no statisticalsignificance (P>0.05).Conclusion①General anesthesia in patients with benign thyroid surgery postoperativebudesonide aerosol inhalation atomization can be faster than using dexamethasonerelieve throat complications.②Preoperative prevention use budesonide aerosol inhalation can effectivelyreduce the throat damage caused by endotracheal intubation of general anesthesia.