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Evaluation On Free-triiodothyronine In Acute ST-elevation Myocardial Infarction In Short-term Prognosis Of Patients Referred To Primary Percutaneous Coronary Intervention

Posted on:2015-07-07Degree:MasterType:Thesis
Country:ChinaCandidate:H ZhangFull Text:PDF
GTID:2284330431951356Subject:Emergency Medicine
Abstract/Summary:PDF Full Text Request
Objective To investigate the short-term prognostic significance of Free-triiodothyronine after primary percutaneous coronary intervention (primary PCI) for acute ST-elevation myocardial infarction (STEMI).Methods102consecutive euthyroid STEMI patients receiving primary PCI were enrolled in this study. The blood was collected between24-hour after primary PCI for Free-triiodothyronine (FT3), N-terminal pro B-type natriuretic peptide (NT-proBNP). Echocardiogram was examined between days5and days7after primary PCI. All patients underwent a follow-up for6months for mortality.Results During the6-month follow-up, there were7deaths in low FT3group, and the survival rate is84.4%and96.5%in normal group (x2=4.493, P=0.034). A positive correlation between FT3and LVEF%was found (y=4.92+40.3, P<0.001) with linear regression analysis, whereas FT3and NT-proBNP negative (y=-1905x+8839, P<0.001). The severity of coronary of two groups have statistic difference (P<0.001).Conclusion In STEMI patients after primary PCI, FT3lever is related to the heart function. low FT3is a predictor of mortality in STEMI patients and can be a predictor of short-term prognoses.
Keywords/Search Tags:myocardial infarctiont, hyroid hormone, percutaneous coronaryintervention, prognosis
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