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Evaluate The Efficacy Of Moxibustion Therapy Yifei Stable COPD Lung And Kidney Qi Deficiency

Posted on:2015-03-20Degree:MasterType:Thesis
Country:ChinaCandidate:H QianFull Text:PDF
GTID:2284330431481998Subject:Internal medicine of traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
Chronic obstructive pulmonary disease (COPD) is increasingly becoming a publichealth hazard disease,manifested in its incidence,prevalence,mortality increased yearby year,gradually increasing the danger of continued concern of the medicalprofession and society. COPD patients with persistent not only cause limitedmobility,it will affect the mental health of the patient,so that patients havedepression,anxiety and other negative mentality,causing negative social effects andcause serious economic burden on the patient’s family. The use of Chinesecharacteristics,therapy COPD,patients in remission on the basis of clinicalsymptoms,enhance the patient’s constitution,reducing the number of acute episodesand improve the quality of life of patients,in the treatment of COPD increasinglyoccupy an important position.Objective: Chronic obstructive pulmonary disease before clinical symptoms ofstable lung and kidney qi deficiency patients,lung function,six-minute walkdistance,dyspnea grading indicators,evaluation Yifei moxibustion with conventionalwestern medicine treatment of chronic obstructive pulmonary disease stabilizationperiod efficacy,and by observing the changes in immune parameters before and aftertreatment to investigate the mechanisms involved in Yifei moxibustion treatment ofCOPD.Methods: A randomized,controlled clinical trial methods. In the population ofpatients with stable COPD lung and kidney qi deficiency,select the60patients met theinclusion criteria were randomly divided into experimental group and controlgroup,the control group received standard treatment program WM test group used inWestern medicine treatment plan based on the specification Yifei moxibustion.Treatment of2.5months. Before clinical symptoms were observed total score(cough,sputum,chest tightness,wheezing,shortness of breath,fatigue,cyanosis),six- minute walk distance,dyspnea grading,lung function,immune function and otherindicators.Results: From the following three aspects Yifei moxibustion with conventionalWestern medicine therapy on lung and kidney qi deficiency of lung disease in patientswith stable chronic obstructive results are as follows:A clinical efficacyThere after treatment,both groups decreased the points (P <0.01),the experimentalgroup than in the control group decreased significantly different (P <0.05);1.1clinicalsymptom score symptom score before treatment was no significant difference (P>0.05).1.2lung function before treatment FVC,FEV1,FEV1%,PEF and other indicators nosignificant difference (P>0.05); After treatment,the test group the indicators wereincreased (P <0.01),the control group FVC,FEV1,before FEV1%compared withtreatment increased (P <0.01),PEF increased obvious (P>0.05);,a significantdifference (P <0.05) the test group than the control group FVC FEV1,PEFincreased,FEV1%increase was no significant difference (P>0.05).Before treatment6MWD was no significant difference (P>0.05)1.3six-minute walkdistance (6MWD); After treatment,both groups6MWD were increased (P <0.01),theexperimental group than in the control group increased significantly different (P<0.05).1.4dyspnea grading grading dyspnea before treatment had no significant difference(P>0.05); After treatment,dyspnea grading test group were significantly different (P<0.01) improvement compared to the control group.2immune parameters2.1and10normal (healthy group) comparison,COPD patients with CD3+T,CD4+T,CD8+T,CD4+/CD8+ratio were lower than the healthy group (P <0.05).CD3+,CD4+,CD8+,2.2test group and control group before treatment CD4+/CD8+were not statistically different (P>0.05); groups CD3+increased significantly aftertreatment (P <0.01),between two groups were significantly different (P <0.01); CD4+test group was significantly higher (P <0.01),no significant increase in the controlgroup (P>0.05),comparing the two groups were significantly different (P <0.01);groups CD8+no significant change (P>0.05); groups CD4+/CD8+ratio weresignificantly increased (P <0.01),no significant difference in comparison (P>0.05).3safety index Results There were no significant differences in examination of blood,urine,feces,liverand kidney function and electrocardiogram before and after treatment. No seriousadverse events occurred during the test.ConclusionsAfter the treatment period,both groups of patients in terms of lung function,clinicalsymptoms and signs,dyspnea and exercise capacity grading were improved,includingthe experimental group improved significantly compared with the control group thatcombines Yifei moxibustion therapy on the basis of Western norms for the treatment ofeffective method of stable COPD lung and kidney qi deficiency. COPD patients doesexist abnormal T cell subsets,improve test group after treatment was significantlyhigher than the control group,believes the development of COPD disease may beassociated with cellular immune dysfunction,regulating cellular immune function maybe Yifei moxibustion treatment of stable COPD,lung and kidney qi one effectivemechanism permits.
Keywords/Search Tags:obstructive, pulmonary disease, stable, lung and kidney qi deficiency, Yifei moxibustion, T cell subsets
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