The Clinical Analysis Of Chinese And Western Medicine Treatment Of Hospitalized Patients With Pemphigus

ObjectiveThrough analyzing medical records of hospitalized patients with Pemph igus retrospectively, this study was carried out to analyze their clinica1characteristics and features in the therapy of TCM and western medicine, summarize the relevant clinical experience so as to further improve the t raditional Chinese and Western medicine’s diagnostic and therapeutic leve1of Pemphigus.MethodsThrough a retrospectively study of medical records of pemphigus patie nts who were treated in the Department of Dermatology in Guangdong Provin ce Traditional Chinese Medical Hospital from2004to2013,this analysis c ontent includes:general imformation, onset symptoms, clinical manifestation s, complications, TCM Syndromes, treatment of traditional Chinese and Weste rn medicine, prognosis and the death cases, summarize the clinical experien ce.ResultsThis study collected imformation of100cases,43male cases,57fema le cases, whose ratio shows no significant difference. The average age of onset was55.20±18.08years old. Among those cases,97people used comb ination therapy of traditional Chinese and Western medicine treatment, who se total efficiency reached97%, and the average hospital stay was19.42±11.88days, shows a statistically significant difference in year differ ence. Among100patients, about83%of the patients’disease courses lasted less than1year, the initial symptom of59cases is skin erythematic bli ster, and there are29patients whoshowed simple mucosal damage symptom. E rythema, blister, ulcer, itching, pain were the main clinical manifestati ons of pemphigus. The most common complication that mainly attack skin and lung is infection, Staphylococcus aureus, Escherichia coli, Candida albi cans, Pseudomonas aeruginosa pathogenic bacteria detection rate for the h ighest. This disease is mingled with excess and deficiency syndromes. Most commonly seen symptoms are common spleen deficiency and dampness heat, a ccumulation of damp heat, dampness heat toxic, deficiency of both qi and Yin, damp and hot. Tongue and pulse’s condition ranking according to the frequency is:dark red, red, pink, pale and dark, yellow and greasy(withco ated tongue), yellow(pale yellow), micro greasy coated tongue, white(thin w hite),pale and thickly coated tongue, taut pulse, thin taut pulse, thin p ulse, slippery pulse, taut slippery pulse. Glucocorticoid is the key drug treatment, generally used with immunosuppressive agents, non steroidal an ti-inflammatory drugs, immunomodulator, and immune globulin. All patients were prescribed with traditional Chinese medicine, Chinese herbal medici ne and Chinese patent medicine were mainly used as to treat dampness, hea t, blood stasis, and deficiency symptoms.Conelus ion1. The treatment of TCM and western medicine in patients with Pemphi gus can effectively improve the clinical symptoms, ease the conditions.2. Works done in our hospital to shorten average length of sta y of patients with pemphigus is worthy of recognition, but th ere are still some deficiencies need to be improved.3.The diag nosis of Pemphigus is still challenging, appropriate measures need to be taken to improve the clinical diagnostic level of pathology and i mmunofluorescence, and to avoid missing the timing of treatment.4."Spl een deficiency" and "wet" are important features of Chinese medicine in the pathogenesis of pemphigus. Flexible use of "promoting diuresis and In vigorating spleen" is an important means of Chinese medicine in the treatm ent of pemphigus. Diuresis medicine, antipyretic, tonifying drug and drug s that are used in removing blood stasis syndrome are several kinds of co mmon drugs used in traditional Chinese medicine treatment of pemphigus.5. The treatment to the inpatients of pemphigus is with hormones, immunosupp ressive agents, non steroidal anti-inflammatory drugs combined with tradi tional Chinese medicine and Chinese patent drug, some new treatment metho ds need to be introduced and tried.6. Special i zed examination should increase the lesion area, in order to more formal pemphigus treatment process.