Newly Diagnosed Type2Diabetic Patients With Syndrome Differentiation Type Of Six Meridians And Insulin Resistance,the Correlation Of Islet Function

ObjectiveBy the early diagnosis of type2diabetes by the line four diagnostic data collection and dialectical analysis based on six by syndromes, respectively syndromes patients in each group insulin sensitivity index and islet function and other related assessments, to explore the early diagnosis of type2diabetes six by typing correlation with insulin resistance, between islet function for the early diagnosis of type2diabetes by six objective indicators to provide clinical dialectic.MethodsCollected from September2013to March201493cases of newly diagnosed type2diabetes four diagnostic data for six meridians typing, clinical testing by collecting data such as glucose tolerance test, insulin release experiments, C-peptide release test and evaluate insulin sensitivity indicators such as islet function and insulin resistance index, index of insulin secretion, insulin, C-peptide release area under the curve, insulin doubled amplitude, calculated as the measurement data and count data into SPSS27.0statistical databases to create and carry out analysis, explore the early diagnosis of type2diabetes and six by typing the correlation between evaluation indicators for diabetes six meridians provide theoretical guidance to more objectively with diabetes six meridians provide hair cut herbs basis.Resultsl.Type2diabetic patients were collected in93cases, including one case of solar certificates, certificate12cases Yangming, Shaoyang syndrome in28cases,18cases permit lunar, lunar card33cases,2cases Jueyin card, in order to avoid excessive sample less cause data errors, the study did not permit the sun, Jueyin card cases statistical data 2. At each time point during OGTT among the four groups syndromes of insulin and C-peptide release level comparison:a lunar fasting insulin levels were highest card (P<0.05), Shaoyang syndrome group60min,120min,180min three time points insulin release were significantly lower than the other three groups (P<0.01), no difference (P between the other two groups comparison group>0.05);. between two groups of four fasting C-peptide levels was no difference (P>0.05), Shaoyang syndrome group60min,120min,180min C-peptide release three time points were significantly lower than the other three groups (P<0.05), no difference (P among the other three groups at each time point groups>0.05);.3four syndromes of insulin secretion peak, C-peptide secretion peaks are located120min.Second, among the four groups HOMA-IR compared lunar syndrome group was significantly higher than the other three groups (P<0.05), no difference (P among the other three groups syndromes group>0.05);3. Four syndromes islet B cell function assessment:1.HOMA-0statistical results suggest that:Shaoyang syndrome group HOMA-β value is significantly less than the other three groups (P<0.01), the remaining differences among the three groups (P>0.05);2.AUCI, AUCC statistical results suggest that: Shaoyang syndrome group AUCI, AUCC were significantly lower than the other three groups (P<0.01), no difference (P among the other three groups>0.05);3. IP/10Statistics the results suggest that:each group IP/10≤5, Shaoyang syndrome group, lunar syndrome group<Yangming syndrome group, Shao syndrome group (P<0.05), no difference between the groups with Shao Yang syndrome syndrome group (P>0.05).4. △I30/△G30statistical results suggest that: Shaoyang card<lunar card<Yangming card, Shao card, with statistical significance (P<0.05).Conclusion1.The four groups to lunar highest HOMA-IR syndrome, insulin resistance heaviest, HOMA-IR can be certified as a clinical reference index lunar dialectical.2. The four syndromes, Shaoyang lowest card HOMA-β, insulin, C-peptide release smallest area under the curve, insulin, C-peptide release delayed peak insulin doubled the minimum margin, early insulin secretion lowest level, indicating Shaoyang syndrome lowest islet B cell function, islet cells are damaged the most severe, may reference index as a clinical syndrome Shaoyang dialectic. 3. In this study, statistical analysis of newly diagnosed type2diabetic patients and six by typing insulin resistance and islet function evaluation indicators discussed correlation, and confirmed it has obvious relevance for the early diagnosis of type2diabetes six meridians provide a basis for clinical and research objective reference.