The Study Of Nephrotic Syndrome And Syndrome Differentiation Of Renalase Related

Objectiveto clear the renalase nephrotic syndrome and correlation between syndrome type.Methods1. Case Selection:Kidney April2013to April2014period Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Shenzhen syndrome,40cases detected by elisa renalase concentration, and improve the24-hour urinary protein excretion, blood pressure, blood urea nitrogen, creatinine, CRP and other related inspection and analysis of TCM symptoms relevance. Experiments with male Wistar rats with nephrotic syndrome induced by doxorubicin hydrochloride model renalase urine analysis and blood pressure correlation.2. For all subjects one by one into the register, the test data is entered into a computer database was established.3. Developing statistical analysis plans, according to the plan execution. Choose a reasonable statistical analysis method based on analysis of the nature and purpose of effect indicators. Use Epidata establish a database of the study, the use of MedCalc12.7.0software for statistical analysis.Results1. A kidney consolidated average age of male patients (39±17.02) years, the average age of female patients was (33±15.56) years old, male and female age difference was not statistically significant (P>0.05). In the syndrome distribution inside, the proportion of women in the spleen deficiency largest group, accounting for20%of men in the damp and the largest proportion,25%;40cases of patients with renal ensemble to damp the largest proportion,40%, each no significant differences between the syndromes. 2.24hPR0damp syndrome group compared with spleen deficiency syndrome group, Qi syndrome were significantly higher, statistically significant (P <0.05), spleen deficiency group and the group without Qiyinliangxu significant difference (P>0.05). Hygropyrexia serum urea nitrogen compared with spleen deficiency group, Qi was significantly lower, with statistical significance (P<0.05). Various syndromes creatinine, showed no significant difference (P>0.05) uric acid, cystatin, protein, cholesterol, triglycerides.3. Patients renalase presence of renal comprehensive linear relationship with systolic blood pressure, systolic blood pressure among disease type group no significant difference.(P>0.05). Nosignificant correlation (P>0.05) and systolic blood pressure.4. In the group consolidated renalase concentration in the kidney, at low concentrations, the ratio of the maximum spleen deficiency; concentrations in order to damp the largest proportion; in the high-dose group, with the largest proportion Qiyinliangxu.5. In patients with renal comprehensive prone to backache, fatigue, high concentrationsin renalase also prone to dizziness, headache, dry mouth, five upset hot, such as"hyperactivity" and other symptoms.6. Kidney mechanized animal experiments and clinical studies have appeared positive correlation between serum renalase and systolic blood pressure.Cone I us i on1. Damp24h urinary protein group was significantly higher than other non-damp syndrome group, serum urea nitrogen than other groups.2. Found renal comprehensive TCM and serum concentrations renalase no significant correlation.3. Groups of patients with high concentrations renalase prone "hyperactivity" symptoms.4. Renal comprehensive serum concentrations of renalase positively correlated with systolic blood pressure.