Clinical Observation On The Treatment Of Female Late-onset Acne With ZishenQingXin Method And The Influence On The Patients’ Quality Of Life

ObjectiveTo investigate the clinical efficacy of the therapy of Zishen Qingxin on female patients with late-onset acne, and observe the improvement of life quality before and after treatment. By investigating the facial distribution of lesions in patients with delayed acne, provide evidence for clinical syndrome differentiation; through the investigation of delayed female acne patients’ life quality, and provide a theoretical basis for clinical therapy.Method72patients were randomly divided into2groups, the treatment group36cases, using the method of Zishen Qingxin decoction of Chinese medicine oral,(two times a day); the control group36cases, using oral Danshentong Capsules1.0g bid. Observation of4weeks, Recording the number of skin lesions in detail and using Cardiff Acne Disability Index in two groups on the quality of life before and after the treatment. Two groups were compared before and after treatment of skin lesions and the improvement of life quality.ResultAfter statistical analysis, two groups of baseline data (age, course of disease, the number of skin lesions, CADI score), P>0.05, were comparable. Before treatment in72cases of delayed female acne patients, there are43people with facial skin lesions distribution in the lower part, accounting for58.3%, followed by the right and left. CADI survey found that the average CADI score is6.99, representing moderate influence of the quality of life. The proportion of patients with mild, moderate and severe impact on quality of life were35%,55%,10%. The average score of social functionis is1.92, and emotion scored an average of3.24, perceived severity scored an average of1.83.68cases of late-onset acne in women completed the trial., Compared to observe the clinical curative effect of the two groups after the end of treatment, the effective rate of treatment group is91.7%, and group of Danshentong Capsules have the total efficiency of84.4%, It is no statistical significance between the two groups; the difference of CADI total score before and after treatment, P=0.00<0.01, is significant, compared with two group CADI after treatment, P=0.024<0.05, the difference has statistical significance.ConclusionDelayed female acne patients with facial lesions were mainly located in the lower part, associated with kidney. Acne affects moderately affected the quality of life of these patients, especially in the emotional aspects, impact on the social function is relatively small. Suggest, we should pay attention to female delayed acne patients about the emotional and psychological health. Improvement effect of Method of nourishing kidney Qingxin Decoction on delayed female acne is remarkable, equivalent efficacy with the control group, but in terms of improve the quality of life of patients, is better than Danshentong capsule group.