Analyze Female The ECG ST-t Change And Risk Factors According To Coronary Angiography

[Objective]Coronary angiography is the objective standard to diagnose coronary heart disease. Compared with male patients, we analyze ECG ST-T change and risk factors among female patients with coronary heart disease (CHD) and pay close attention to the female patients, in order to diagnose and treat female patients with CHD. meanwhile provide a scientific theory for prevention strategies.[Methods]Randomly selected from November2012to January2014because of chest pain and electrocardiogram(ECG) ST-T change as primary diagnosis coronary heart disease angina pectoris. who are admitted cardiovascular department of the first affiliated hospital of kunming medical university and further inspected treadmill exercise test(TET) and successfully implemented270patients of coronary angiography (CA) who are divided into CHD group and control group according to the result of coronary angiography(coronary stenosis≥50%would be coronary heart disease positive (CHD)group and coronary stenosis<50%would be coronary negative group).Electrocardiogram (ECG) positive standard:two or more adjacent lead:in80ms after the J point ST segment horizontal or oblique type is down≥0.05mv or T wave is low or inversion.Coronary angiography(CA) positive and ECG positive is ECG positive group and coronary angiography negative and ECG positive is ECG false positive group, coronary angiography positive and treadmill exercise test (TET)positive is TET positive group, CA negative and TET positive is TET false positive group.Analyze situation between single coronary artery and multivessel lesions among female CHD and male CHD according to the coronary artery lesion number, we comparatively analyze angina pectoris classification of CHD between women with CHD and male with CHD, according to clinical classification (unstable angina pectoris and stable angina).we comparatively analyze positive and false positives of ECG between female patients and male patients base on the results of ECG and CA. and analyze positive and false positives of TET between female patients and male patients according to results of CA and TET. Comparatively analysis risk factors between female CHD patients and male CHD patients. All data using SPSS17.0statistical software to analyze data, categorical data is expressed as a percentage of the chi-square test or the exact probability method, the measurement data with standard deviation.the main indicators use normal distribution test and use t test on comparison between the two group. Analyze independent risk factor for female of CHD by Logistic regression analysis risk factors of women of CHD and control group.Inspection level a=0.05, p<0.05for the difference is statistically significant.[Results]125female patients,positive electrocardiogram (ECG) is66cases (52.8%), false positive59patients (47.2%),145male patients, electrocardiogram (ECG) positive94cases (64.82%).false positive51cases (35.7%).women TET of positive group51cases.false positive group19cases, sensitivity77.27%, specificity62.75%, male patients of TET positive86cases,TET of false positive group35cases, sensitivity91.49%.specificity of31.37%.Female patients with (CHD) are66cases, stable angina37cases,unstable angina29cases, male patients with CHD94cases, stable angina27cases, unstable angina67cases.women’s single lesion of CHD47cases,multivessel lesions17cases,male with single lesion of CHD28cases, multivessel lesions66cases, age distribution of male and female with CHD, female are27-55years old,11cases (18.64%),55cases (83.33%)≥56years old,male with (CHD) are29to45years old.29cases (43.94%),≥56years old65cases (69.15%).Female patients with CHD, hypertension are51cases (77.27%),diabetes32cases (48.48%). dyslipidemia9cases (28.79%), high uric acid42cases (63.64%),smokers3cases (4.55%).control group:hypertension5cases (8.47%).diabetes31cases (52.54%),dyslipidemia10cases (16.95%), high uric acid25cases (42.37%), smokers are (3.39%).the male with CHD. hypertension63cases (67.02%), diabetes21cases (22.34%), dyslipidemia33cases (35.11%). high uric acid65cases (69.15%), smoking 86cases (91.49%).(1) This study find application of ECG ST-T change diagnose angina pectoris of CHD among270cases of patients,whose positive rate is only59.26%, in which women are52.8%. male are64.82%. so it is not fully diagnosed CHD according to ST-T change,especially in female patients.(2) Women compared with male patients, Female CHD with T wave change.stable angina,coronary single lesion are more than male’s patients, the male CHD with ST changes, unstable angina, multivessel lesions are more than female’s patients(3)160cases CHD, female CHD patients compared with male CHD patients female age are older than male’s.≥56years old age group are more(4) female CHD compared with control group, uric acid, cholesterol,QTC mean are higher,the proportion of high blood pressure, and high uric acid are more and with two or more risk factors among female CHD patients(5)female CHD compared with male CHD.the proportion of women with diabetes are more, male smoking rate are more.risk factors of women with (CHD) and control group by Logistic regression analysis, hypertension, dyslipidemia,high uric acid, the age are independent risk factors in femaleCHD patients, diabetes also play a role on the pathogenesis on CHD.[Conclusions]This study find that application of ECG ST-T change diagnose CHD angina pectoris.whose positive rate is only59.26%.Women are52.8%, male are64.82%. ECG is convenient,easy,noninvasive,repeatable in the diagnosis CHD angina patients.The positive rate of diagnosis is deviation compared with commonly formed concept especially women,particularly women who are before menopause.Compared with male ECG diagnosis.female CHD is higher false positive rate.while TET diagnosis CHD is higher negative value.and T wave change.stable angina,coronary single lesion are more than male’s.The male CHD with ST changes, unstable angina, multivessel lesions are more than female’s.Female CHD patients compared with male CHD patients, female age are older than male’s.Uric acid,cholesterol,QTC mean are higher.and the proportion of high blood pressure and high uric acid are more and with two or more risk factors among female.And hypertension, dyslipidemia.high uric acid, the age are independent risk factors in female CHD patients.diabetes also play a role on the pathogenesis on CHD and female patients often have two or more risk factors.So actively prevent the occurrence of cardiovascular disease,early prevent, control or eliminate the risk factors, and reduce incidence of CHD,especially for women with a greater significance.