An Analysis Of Clinical Characteristics Among Lung Cancer Population Nearly Five Years

Background and Purpose: Lung cancer, namely primary bronchogenic carcinomawas a clonal disease which mutated from the cell. In recent years, the morbidity andmortality rates of lung cancer significantly increased, had become the largest cancer inChina, and also had became the highest morbidity and mortality rates of malignanttumors in the world. The therapy of lung cancer had received widespreadattention around the world. This paper was to analysis the clinical features of lungcancer which could improve the early diagnosis rates and prognosis.Method: A retrospective analysis of the data of490newly diagnosed lung cancerpatients who had been admitted to our hospital from January2009to November2013.To analysis and discuss the data of gender, age, smoking history, pathology, clinicalsymptoms, CT performance of fiberoptic bronchoscopy performance, serum CEA andmetastasis of the patients.Results:490cases of lung cancer included318male patients and172femalepatients, the ratio of1.85:1, the incidence of male patients was significantly higher thanfemale(P＜0.05). Pathological types had adenocarcinoma, squamous cell carcinoma,small cell carcinoma, large cell carcinoma, and the other types. Adenocarcinoma wasmost pathological types between male and female patients. There were more male thanfemale patients in small cell lung cancer group, but there were significantly more femalethan male patients in adenocarcinoma and large cell lung cancer groups. Patients agedbetween25and91, with an average age of59.23±15.23. All patients were divided into≤50,51-60,61-70,＞70groups, the incidence between the four groups had no statisticsdifference. There were more squamous cell lung cancer in＞70group, which hadstatistics difference. Smoking was still a significant risk factor for lung cancer, thesmoking rate of male lung cancer patients was55.03%. The clinical symtoms varied,but had no specificity, included cough, shortness of breath, fever, weight loss and othersystemic manifestations, chest pain, hemoptysis and bloody sputum, and no clinicalsymptom was14.08%. CT showed that mainly had lung mass and hilar mass,60.2%and38.78%respectively, and followed by obstructive pneumonia and atelectasis,pleural effusion, shadow and nodules which diameter <1.0cm. Fiberopticbronchoscopy were divided into normal type, luminal growth type, luminal stenosistype, tube outer wall of oppression and infiltrative type. Among them the most commontype was luminal growth type, the normal and luminal growth types were more commonin squamous cell lung cancer group, the infiltrative and luminal stenosis types were ,more common in adnocarcinoma group. The detection of Serum CEA increased whichwas mainly in adenocarcinoma. There were269patients(54.90%) who were diagnosedwith lung cancer when accompanied by transfer, patients with small cell lung cancerand age≤50years had the higher transfer rate which had statistics difference.Conclusion: More male than female patients with lung cancer, but the incidenceof female patients exhibits ascending trend. No significant differences between each agegroup of lung cancer, the incidence is getting younger and younger. Smoking is still asignificant risk factor for lung cancer, especially for sqamous cell carcinoma. Theclinical symtoms and CT manifestations have no specificity. Luminal growth type is themost common type of fiberoptic bronchoscopy. Serum CEA detection has higherreference value to the diagnosis of adenocarcinoma. Lung cancer is found whenaccompanied by transfer, and patients with small cell lung cancer and age≤50yearshave the higher transfer rate. In short, to enhance the understanding of the clinicalfeatures of lung cancer, and to pay attention to lung cancer screening, ealy diagnosis andtreatment can prolong survival and improve the quality of life of patients.