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Clinical Study Of Microwave Coagulation Therapy For Hepatic Hemangioma

Posted on:2015-03-03Degree:MasterType:Thesis
Country:ChinaCandidate:S F LvFull Text:PDF
GTID:2284330422973285Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective: Through the comparison of percutaneous microwave coagulation andoperation resection of giant hepatic hemangioma treatment, analysis the advantages anddisadvantages of microwave coagulation in treatment of huge hepatic hemangioma,provide new method for the treatment of huge hepatic hemangioma, new ideas.Methods: According to the hospital from2011October to2013betweenDecember hospitalized patients with hepatic hemangioma were analyzed, studied56selected lesions larger than5cm in diameter≤15cm patients; Among all patients aged23~67years old, average age40.5±9.1years, including18cases of male patients,38female patients,42cases had single tumor,15cases of multiple tumor, a total of80vascular tumor, the tumor size was7.2±1.7(5.0~13.2) cm;32patients by PMCTtreatment, including11cases of male patients,21female patients, mean age39.6±9(23~67); a total of50lesions.24cases underwent operation resection,7males,17females, mean age41.6±9.6(24~61); a total of30lesions. The PMCT component isnot cured lesions, in patients consent hospitalized during the two microwave curing, so asto achieve the purpose of complete cure. All selected patients in hospital, includingpatient characteristics, tumor size, operation time, intraoperative bleeding volume,postoperative complications, hospital stay and other indicators were collected, andstatistical analysis was performed using statistical software SPSS17.0.Results:56cases of lesions, a total of80patients with massive hemangiomalesions in5cases>10cm in diameter,3patients for multiple lesions in5patients,2cases of single lesions10cm in diameter of51cases, PMCT group of29cases, surgicalremoval of the group of22cases.The following10cm lesions in patients with clinical data analysis found that,bleeding and hospitalization days in the PMCT group, operation time, intraoperative (65 ±17.9min,14.1±4.8ml,8.8±1.7day) were significantly lower than operation group(131.8±31.9min,572.7±264.0ml,13.5±2.8day), there is significant differencebetween two groups (p1<0.01, p2<0.01, p3<0.01). Analysis of blood transfusion rateof two groups of patients after, PMCT group (1/29) with operation resection group (10/22)has obvious difference (p <0.01), with statistical significance. All operation resectiongroup patients were removed completely, operation underwent color ultrasoundexamination found no obvious residual lesion, group PMCT after color ultrasoundshowed that38lesions were treated with PTCM, lesions were completely destroyed,accounted for86.4%(38/44);6were hospitalized during the two cured, postoperativecolor ultrasound show5lesions were completely destroyed, accounted for83%(5/6),1lesions of blood lost, a small amount of residual lesions.On the analysis of5cases of10cm≤15cm, PMCT group accounted for3cases,2cases with multiple lesions,1cases, there were6lesions,3lesions with diameter>10cm; microwave coagulation therapy was found after10cm lesions were small residual,need the two curing, due to peritoneal effusion in1patients,1patients with chronichepatitis B, for the first time after microwave treatment had abnormal liver function, notthe two cured,1cases cured after two times after the blood supply completelydisappeared, but there is still a small amount of residual lesions.The PMCT group patients were followed up for6~12months, follow-upabdominal CT revealed the diameter of tumor shrank to75%,2patients with lesions ofblood supply of tumor disappeared, no obvious increase complete remission in all cases,abdominal pain, bloating and other symptoms. Correlation analysis was performed on thepatients in group PMCT hemangioma diameter and microwave curing time, and multiplelesions in the maximum lesion diameter; results suggest huge hemangioma lesions ofmicrowave curing time needed and lesion diameter was positively correlated (r=0.585, p<0.01).All the cases in addition to surgical resection group1patients postoperativeincision infection, give debridement dressing, secondary suture processing, the remaining cases no adjacent viscera damage occurred, also did not find any obvious gastrointestinalperforation and other complications, postoperative none of the patients died.Conclusion: The findings of this study for hepatic hemangioma diameter less than10cm, PMCT and surgical operation is a safe and effective method. But the PMCT in thetreatment of10cm following hemangioma more minimally invasive, more convenient.For hepatic hemangioma10cm above, PMCT inadvertently satisfied effect, should becareful to choose. Microwave curing time was prolonged with increasing vascular tumordiameter.
Keywords/Search Tags:hepatic hemangioma, Microwave Coagulation, excison, Minimallyinvasive
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