Clinical Effect Of Different Operation Methods For Endometrial Cancer In Stage One

Objective: The outcomes and postoperative complications with alternative surgicalprocedures for stage Ia endometrial cancer are discussed and compared here. This is toexplore the clinical basis for reasonable individual treatment, to increase the survival rate, andto improve the quality of life.Methods: Sixty-eight postoperative cases with stage Ia endometrial carcinoma fromMarch2001to December2006are reviewed and retrospectively analyzed. The patients weredivided into two groups according to different surgical procedures performed. Thirty of themundergone extro-fascia total hysterectomy and adnexectomy are group I. The group IIincludes the rest38patients received additional pelvic lymphadenectomy as well as the sameabove procedures. The survival rates and peri-operative conditions in two groups arecompared by statistical analysis.Results:The5year survival rates are96.6%in group I and97.3%in group IIrespectively without statistical importance(P>0.05). The recurrence rates are3.33%and2.63%with no significant difference between the two groups(P>0.05). However, the timeand blood loss in operation, hospitalization, incidence of postoperative complications andquality of life(P <0.05) are dramatically different in two groups with statistical importance.There is no obvious impact of pelvic lymph node removal to the curative outcomes.Conclusion:1. The extro-fascia hysterectomy and adnexectomy is acceptable for stage Ia endometrialcancer.2. Removal of pelvic lymph nodes in patients with stage I diseases is helpful to clarifythe surgical and pathologic stages.3. The pelvic lymphadenectomy itself is not the necessary curative procedure. Extensiveoperation may not significantly increase the survival rates.