The Change Of Thyroid Nodule Disease With Before And After The Universal Iodization In Ningxia Area

Objective1, To observe the change of thyroid nodule and how to change before andafter the iodine in Ningxia area.2, To strengthen the understanding of the malignant nodulesclinical features. through the comparative analysis to the benign and malignant thyroidnodules. Methods Select the medical records by surgery patients of the ningxia medicaluniversity hospital1988-1993and2005-2010, Pathological results confirm for thyroid nodule(TN) patients. Collect975cases before the iodine (1988-1993) and2375cases after the iodine(2005-2010). The selected cases have perfect preoperative examination, and have surgerypathological results. Using the following statistic mathods: analysis of variance、χ~2test and ttest by the SPSS13.0(Statistical Package for the Social Science) software. Results (1)3350cases of object before the USI29.1%, female/male3.2:1; After the USI70.9%, female/male3.4:1, female than men. Age decreased, and the course shorten. National and thyroid functionwere all no statistical difference.The incidence rates were higher in the area along the yellow(χ~2=6.910P=0.009).40~50years old was the largest,<30and30~40years old groupincreased,50~60and>60years old group down.With increased year, Armour and thecancer show clear ascendant trend.(2) Thyroid malignant nodules detection rate increased.The gender and national were without obvious difference. Malignant nodules group averageage reduction.30~40years old was the highest. Course and days in hospital obviouslyreduced. TSH in the normal range, the malignant nodules were larger than the overall average.The proportion of thyroid papillary carcinoma (PC) increased, thyroid follicular carcinoma(FC)was down. Through the99Tc scanning, no functional nodules was occupied80.7%, which accounted for5.08%of thyroid cancer.5cases hot nodes and181cases temperaturenodules were benign lesions. The onset of left and right side was no significantdifferences.According to the Logistic regression analysis, young, with micro calcium, coatingis not complete, solid, malignant nodules may be more likely. Conclusion1.With pathologyresults for gold standard,after the USI ten years，The incidence of TN was increase, andthere is a trend of getting. As a specialist, it is important to improve the early screeningconsciousness and the early prevention and treatment. At present, B super is the mostadvantage of all the check, it can be used as a routine inspection In the screening stage.2.Thenodules of age light, micro calcification, not the capsule, solid, low echo may be malignant.Above is the risk factors of malignant nodules, we should be highly vigilant. At the same time,we should try to avoid unnecessary surgery, On the one hand relieve pain, on the other handalso save the national health resources.3. In the future,More attention should be paid to thelow levels of papillary carcinoma diagnosis and treatment.4. Public health problemintervention strategies is not unchangeable, According to the monitoring results adjustedaccordingly. This research found: the nodules morbidity of the area along the yellow was notincrease, it is should take into account. As for how to make changes, it Depends onepidemiological survey.