Screening Of The Effective Ingredients Compound Of Mongolian Medicine Compound And Research Of Its Treatment Function On Dairy Cow Mastitis

Mastitis in dairy cows has been claimed as one of the most obstinate disease in the cow production,as well as in the clinical treatment. Treatment difficulties and recurrence were the most challenging problems in current stageWestern medicines have been using as a treatment, however, the residue for the antibiotic, chance of recurrence, drug resistance, and etc. are the problems urgently to be solved. Mongolian veterinary drug as new method with no toxic side effects, no chemical residue,and no drug residence needs to be well developed. Over the same period,on the base of screening out the antibacterial compound and anti-inflammatory ingredient compound.Screening out ingredient compound of Mongolian medcine with either antibacterial or anti-inflammatory through the method of orthogonal.To deal with the mastitis through injection of pipe of papilla,main experiments are conducted:1. Regard the antibacterial in vitro and anti-inflammatory immune as the index, screen out the ingredient compound of Mongolian medcine with either antibacterial or anti-inflammatory through the method of orthogonal.2. Detect the blood leukocytes using flow cytometry show that ingredient compound of Mongolian medcine can improve the rate of CD3+T;CD4+/CD8+T; CD21+B obvious.3. The result of hormone and cytokines using elisa show that Mongolian compound can improve the content of ATCH; CORT; E; IL-1β; IgG; NAGase obvious.4. Ingredient compound of Mongolian medcine can decrease the amount of SCC.5. Ingredient compound of Mongolian medcine can decrease the leukocyte of blood.Show that ingredient compound of Mongolian medcine can cure cow mastitis through improving the immune of the cow.Conclusion:Ingredient compound of Mongolian medcine could cure the mastitis effective, and can improve the immunity of the cow.