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The Research And Development Of Device For Batch Making W-Pt Micro-Nano Thermocouple

Posted on:2016-08-12Degree:MasterType:Thesis
Country:ChinaCandidate:J Q WangFull Text:PDF
GTID:2272330503477842Subject:Biomedical engineering
Abstract/Summary:PDF Full Text Request
Temperature is one of the most important parameters of life. The moderate distance berweem the earth and the sun keep the earth an annual average temperature around 15 degrees, whilch is crucial for life to produce and reproduce. Temperature plays a significant role in cell metabolic activity in the basic unit of life.The measuring of single cell temperature change is a new rising technique in 1990s. The rapid improvement of microfabrication technology makes developing measuring tools for temperature studies of single cell possible. The micro-nano thermalcouple draws a lot researcher’s attention for its low cost and convenient fabrication and high precision. It’s reported that the thermalcouple based on micropipe and the coaxial thermalcouple based on two metals are commendably applied in the single cell temperature measuring with their good cone-shape and solid base material. W-Pt micro-nano thermalcouple is a coaxial thermalcouple based on wolfram and platinum. It’s reported that W-Pt micro-nano thermalcouple match the requirements of single cell temperature measuring for its high Seeback coefficient, fast response and good biocompatibility. However, the process of making W-Pt micro-nano thermalcouple is time-consuming and the performance is not very stable. These shortcomings limit the research.The results of single cell temperature measuring depend highly on the performance of W-Pt micro-nano thermalcouple. Generally speaking, the size of its tip shoud be samll enough to insert a cell (at least less than 500nm), the cone angle under 20°is commendable, and a high Seeback coefficient will be suitable(4.0-10.0μV/K). So developing a device for quickly and steadily making W-Pt micro-nano thermalcouples in a bulk volume will strongly improve the research of singal cell temperature measuring.It introduces a set of facility for making W-Pt micro-nano thermaolcouple based on the STM32 platform and android mobile phone platform. User can steadily make W-Pt thermalcouples in a bulk volume. At the same time, user can monitor the key parameters data of fabrication process gathered and displayed by android mobile platform in real time. This thesis covers three main aspects of developing the device. The first two chapters introduces the basic principle and fabrication method of thermocouple for single cell temperature measuring. It describes the detailed analysis of the device structure and the design of function, giving a distinct overall appearance of this device. The second part is about the hardware and software of the device electric control system. In the third part, it introduces the actual test results by analysing the performance of the thermaolcouples made by the device. The results shows that the performance of W-Pt micro-nano thermalcouple is stable. The tip radius of curvature is about 300nm, the cone angle is less than 18°, the Seeback coefficient is 4.0-8.0μV/K. The thermaolcouples made by the device can be applied in single cell temperature measuring research. The device improves the research by supplying W-Pt micro-nano thermalcouples with steady performance.
Keywords/Search Tags:Single Cell Temperature Measuring, W-Pt Micro-Nano Thermalcouple, Device Development, STM32, Android Software Development
PDF Full Text Request
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