The Study Of Noninvasive Intracrannial Pressure Mesurement Method Based On The Bioelectrical Impedance

Brain diseases, such as traumatic brain injury, brain tumor, brain hemorrhage,hydrocephalus, intracranial inflammation and so on, can cause an increase in the volumeof the cranial cavity matter, which will result in intracranial pressure keeping above2.0kPa (15mmHg), thereby causing a corresponding syndrome. This is called IncreasedIntracranial Pressure, or IIP. Increased intracranial pressure is a common clinical andpathological syndrome of neurosurgery, which can cause cerebral hernia, makes thepatient died due to respiratory and circulatory failure. So it’s very important to diagnoseincreased intracranial pressure timely and treat it properly.Nearly thirty years, developing a new measuring technology for measuringbioelectrical impedance, which is called Bioelectrical Impedance Measuring Technology,or BIMT. The measuring systems based on this technology are inexpensive, the operationon them is simple, non-invasive, safe and assured. The application prospects is very broad,which attracted high degree of attention of clinical medicine and biomedical engineeringacademic at home and abroad.This paper designs a non-invasive intracranial pressure measurement system basedon bioelectrical impedance method. The system chooses AD5933as impedancemeasurement chip, micro-controller STM8S208MB as core controller. The interactiveinterface is compile by LabVIEW. The measurement data is uploaded to upper computerfor display and storage via USB port. In this paper, the system is used to make thesingle-frequency, multi-frequency pure resistance and human trials tests. The experimentresults of pure resistance show that this measuring system having high accuracy andstability; the experiment results of human show that the single-frequency andmulti-frequency measurements of cerebral impedance amplitude obtained using thissystem are consistent with the theoretical value, so it can be regarded as reference valuesin the routine testing of intracranial pressure, which has played an exploration role in therealization of non-invasive measurement of intracranial pressure.