Design And Synthesis Ofa Flavone-based Fluorescent Probe For Detection Of Hydrazine

There are a wide variety of organic pollutants existed in the environment. When their concentration or content exceeds the threshold limit,they may pose a threat to the environment and human health. Therefor, looking for some excellent and real-time detection approaches is of great interest and importance.Hydrazine(N2H4) is a highly raective base and reducing agent, widely used in the fields of chemical industries, pharmaceuticals, aerospace, metal anticorrosion and so on. However, hydrazine is volatile, mutagenic and carcinogenic toxic. Because of the extensive use of hydrazine and its fine water solubility, so durying the proscess of manufacture, usage and disposal, hydrazine can easily cause severe damage to the ecological environment and human healyth. Therefore, to explore more and more reliable and accurate analytical approaches for the detection of hydrazine is a significant issue. So far, several conventional analytical methods for detecting hydrazine have been reported, such as chromatography, electrochemistry, spectrophotometry and chemical titration. Compared with these methods, fluorescent probes based on fluorescent techniques have gained increasing attention because of its high specificity and sensitivity, easy of operation.In view of all above, the fluorescent probe DBF based on flavonnids was designed and synthesized for detecting hydrazine. The probe DBF were synthesized using o-hydroxyacetophenone and dimethylaminobenzaldehyde as starting materials and its structure was characterized. Then its spectroscopic properties and proposed mechanism to detecting hydrazine were studied.The main conclusions were made as follows:(1) The synthetic method was easy to contral, had a desirable yield.(2) Spectrum test showed that the probe DBF exhibited good sensitivity toward hydrazine with a detection limit of 0.68 μM. Metal ions and anions led almost no notable changes to the fluorescent intensity. And not only that, nitrogen-containing small molecule compounds also did not interfered during the detection. The results demonstrated that probe DBF possesses excellent selectivity toward hydrazine.