| In the knowledge economy, there is no doubt that education becomes an important factor to economic development. Higher education is an important part of the educational process, and a critical factor of affecting economic growth. With the government’s emphasis on higher education, the government adopted some reform measures, and adjust the distribution of higher education for several times, but the effect of the adjustment is not obvious. East, central and western higher education gap is still large. What impact is regional distribution of universities to economic growth and how to adjust the layout of colleges and universities has become an important issue.This paper reviews the research results at home and abroad, combined with measurement of economic growth theory and space econometric theory, add the space factor to the impact of the higher education on economic growth, and build a spatial econometric model. We collect the associated variable cross-section data of218cities which have undergraduate colleges, using factor analysis of SPSS statistical analysis software to classify the variables, and get three factors last, namely the size of universities, the investment of colleges and universities, the output of colleges and universities. Using GeoDa the spatial measurement software build the spatial error model of the eastern, central and western regions based on the front of theory, comparing the results of the three regions’model to analyze regional differences. We draw the impact of the size of universities, the investment of colleges and universities, the output of colleges and universities to economic growth, GDP’s spillover effects between neighboring cities, and the obvious leading function from surrounding cities with the size of universities, the investment of colleges and universities, the output of colleges and universities of this locality. Finally in connection with findings, summarizes the optimal adjustment countermeasure of the colleges and universities’layout. |