Spleen Soup Combined With A Small Dose Of Olanzapine Heart Deficiency Type Insomnia Discussion Effect

Background:As the rhythm of life speeding up, people’s stresses of life increasing,up to the old, down to the small, are plagued by insomnia in different degrees. Insomnia is not serious illness, but can make people to reduce the quality of life. Have a good sleep, has a great influence on people’s health, so to improve patient’s sleep is a pressing task. The Chinese medicine therapeutics on insomnia is less adverse reaction and tolerance. And it could regulate body, search for the primary cause of disease in treatment. If combination of Chinese and Western medicine therapeutics on insomnia can make the two sides complement each other. Not only can rapidly improve the symptoms of insomnia, but also can vary from person to person. Pay attention to etiological and pathogenesis. The author’s mentor likes to use small dose of olanzapine with Chinese medicine treatment of insomnia, and the curative effect is significant. Olanzapine is not guidelines recommended by the routine treatment of insomnia drugs, but after the long-term use of the conventional sedative hypnotic drugs, it could surface side effects such as drug dependence, bounce and cognitive impairment. Small dose of olanzapine can not only improve the feeling, at the same time has a calming effect. Studies have reported that small dose of olanzapine can decrease the times of sleep and wake up at night and increase total sleep time, sleep efficiency, daytime function and satisfaction improved significantly. And small dose of olanzapine on cognitive function in patients with no damage, long-term use of dependence, no rebound after drug withdrawal. The author found that the insomnia of deficiency of both heart and spleen pattern was more, so in this study, cases insomnia of deficiency of both heart and spleen pattern as the research object.Objective:To evaluate the curative effect of the intervention spleen-restoring decoction intergrating with small dose of Olanzapine of insomnia of deficiency of both heart and spleen pattern.Methods:We used small dose of olanzapine combined spleen-restoring decoction with pure spleen-restoring decoction all30cases of control insomnia of deficiency of both heart and spleen pattern, cases patients treated for2weeks. Before and after treatment were applied in Pittsburgh sleep quality index (PSQI) rating scale and TCM syndrome scale, observe the clinical curative effect and TCM syndrome curative effect.Results:The total effective rate of the treatment group was66.67%, the control group was67.86%, the difference was statistically significant (P<0.05), suggesting the comprehensive curative effect is better than that of the treatment group in the control group. PSQI scores, the comparison between the two groups after treatment of PSQI total no statistical significance (P>0.05), two groups of PSQI score improvement similar. PSQI each factor comparison in the group, the treatment group in sleep quality, sleep latency, sleep time, sleep efficiency, improve the sleep disorder;The control group in sleep quality, sleep latency, sleep time, sleep efficiency, daytime dysfunction has improved, PSQI between each factor groups has no statistical significance (P>0.05). Tip two groups of patients in the sleep quality, sleep latency, sleep time, sleep efficiency, sleep disorders are improved, but remains close. TCM syndrome, the treatment group in fatigue, palpitation, dizziness, inappetence, improved the stay; The control group in palpitations, dizziness, fatigue has improved. In addition to the dizziness, the rest of the several score comparison between the two groups has no statistical significance (P>0.05). Tip in the two groups after treatment in patients in the palpitations, fatigue, are improved, but remains close. Treatment group giddy score before and after treatment the mean difference of0.43, in the control group giddy score before and after treatment the mean difference of0.86, so the curative effect with respect to dizziness treatment group is better than the control group.Conclusion:The treatment of spleen-restoring decoction had obvious clinical efficacy on treating insomnia of deficiency of both heart and spleen pattern. The curative effect of spleen-restoring decoction intergrating with small dose of Olanzapine was not good as the treatment of spleen-restoring decoction,needs further research.