| [Research Purpose]The purpose of this research is through the breast cancer patients’ clinical symptoms, quality of life, grade of anastrozole-related adverse reactions and tumor markers, blood lipids level to make a clear conclusion about Warm yang and tonify qi therapy to improve their clinical symptoms and quality of life, reduce anastrozole side effects and other sides. The ultimate goal is to improve the clinical effect of traditional Chinese medicine(TCM) treatment and evaluation standard of TCM, to provide clinical basis for TCM treatment decisions and standardization of TCM efficacy evaluation system of breast cancer.[Research Methods]It is a prospective study, collected from February2013to February2014/treatment in BUCM Dongfang Hospital oncology, breast cancer patients who is met the inclusion criteria. Give them Warm yang and tonify qi therapy. Record scores of clinical symptoms, quality of life and anastrozole adverse reactions before and after TCM treatment, comparing changes in these indicators; Investigate the inhibitory effect of Chinese medicine for cholesterol, overweight/obesity and other risk factors associated with breast cancer recurrence. Statistical analysis using SPSS17.0software for calculations.[Results]1To improve clinical symptoms, the symptom scores before and after treatment calculations show that healed0cases,3cases markedly effective, effective in31cases and invalid6cases. TCM total effective rate was85%. Among this symptoms, chills, fatigue, less gas, fatigue, diarrhea, sweating, loss of appetite and insomnia had a significantly improved.2By observing universal table SF-36form and breast cancer specific scale FACT-B table showed that with this treatment, SF-36table’s scores increased from112.11±14.11points to120.48±11.63points; physiological conditions, social/family status, emotional status, functional status, and additional attention parts scores in FACT-B table improved, and the body conditions and emotional status of the patients improve higher than other parts. Upon examination, all P<0.05, the result was statistically significant. Patients’main aspects of life with TCM treatment are improved.3It can reduce the side effects of anastrozole. Anastrozole side effects scores before treatment was9.38±4.57points, after treatment it reduce to6.13±3.12points, with t-test, P<0.05, the difference was statistically meaning.4Patients’Lipid level indicators after3months medicine treatment were TC5.10±0.85mmol/l to5.00±0.81mmol/l; TG1.71±0.52mmol/l to1.64±0.54mmol/l; HDL1.46±0.42mmol/l to1.51±0.38mmol/l and LDL3.10±0.68mmol/l to3.02±0.68mmol/l. Lipid levels after treatment than before was decreased. The difference was statistically meaning.There is a possibility that TCM can stable lipid levels and reduce the risk of hyperlipidemia occurs.5Patients’body mass index(BMI) before treatment was23.45±3.22kg/m2, with TCM treatment3months, the BMI was23.28±2.95kg/m2, through t test, P>0.05, the difference has no significant.[Conclusions]1Warm yang and tonify qi method can effectively improve the yangqi deficiency syndrome type and reduce the symptoms of breast cancer patients, the total effective rate was85%;2Warm yang and tonify qi method can significantly improve patients’ quality of life.3Warm yang and tonify qi method can reduce anastrozole nagetive effects in endocrine therapy;4Warm yang and tonify qi method can reduce patients’lipid levels in long-term using anastrozole;5Warm yang and tonify qi method can stabilize body mass index in breast cancer patients;... |
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