Study Of Factor Characteristics Of Ischemic Leukoaraiosis Vertigo Syndromes

Objiective Leukoaraiosis(LA) is commonly seeing in all kinds of the pathological process of the cerebral diseases. The simple LA is a non-specific imagenolgy diagnosis of the lack of perfusion of the brain, and the diagnostic criteria of LA is mainly due to the image of CT or MRI and LA performs with non-specific symptom. In the clinic practice, LA is known as the negative correlation with the perfusion of the brain, which is the main factor leading to the simple LA. The vertigo is the normal symptom of the LA, and turning to the further development, the cerebral infarction, cerebral hemorrhage and vascular dementia will perform. All these diseases will load the heavy burden to families and society. The therapy of LA at the early stage is a very critical work. Chinese medicine has accumulated rich experience on treating vertigo. To research the characteristics of TCM syndrome factors, and to make sure the therapy of the vertigo of ischemic LA, this research is preliminarily to conclude the symptoms and the syndrome factor. And, according all above, we make the therapeutic method and the prescription, and validate the efficacy of the treatment.Method1.Collection of119cases of ischemic LA of vertigo in the Dongfang Hospital of Beijing University of Traditional Chinese Medicine. Conclude the symptoms of the cases and obtain the occurrence rate of the symptoms. According to the Symptomatic partial of traditional Chinese medicine diagnosis and treatment technology, the two associate chief physicians or archiaters judge the symptom factor of the119cases, obtain the ischemic LA of vertigo.2. We use Safflower, Pseudo-ginseng, Pinellia ternata, Pericarpium citri reticulatae, Lumbricus, turtle shell and et al to reduce phlegm, invigorate the blood and remove stasis and to treat the21cases of ischemic LA of vertigo. Record the grade of the vertigo using visual analogue scale—the minimum is0and the maximum is10—before and after this3-month therapy. Obtain whether the symptom of vertigo will get better or not. Record the grade of relative symptom—0is never,1is occasionally,2is often,3is sustaining—before and after the therapy. Obtain whether the symptoms about the vertigo will get better or not.Result1.The first of the symptoms is dizziness, and its number is119and its proportion is100%. The second symptom is not clear, the number and proportion of which are60and50.4%. The result we can conclude is that the dizziness and not clearness are the main symptoms of the LA vertigo, and these symptoms are the typical symptoms of the chronic low-perfusion of the brain. In the119cases, The percentage rates for8syndrome factors are as follows:Phlegm58.0%, Stagnation of blood52.9%, Yin deficiency30.3%, Blood deficiency24.4, Stagnation of Qi18.5%,, Qi deficiency17.6%, kidney essence deficiency14.3%, Wind12.6%. In the119cases, the number of deficiency syndrome factor is15,the number of excess syndrome factor is46and the inclusion syndrome is58. The proportion of two-syndrome-factor inclusion is58.8%, and the proportion of inclusion of phlegm and blood stasis is34.5%.2.Treating21cases of inchemic LA of vetigo. Using the two grades of vertigobefore and af ter the therapy to T test, we can get that t=6.478, df=20, p (bilateral)<0.001. The vertigo symptom takes a turn for better. Using the two grades of relative symptom about vertigo before and after the therapy to T test, we can get that t=6.269, df=20, p (bilateral)<0.001. This therapy is absolutely effective to the LA vertigo.Conclusion The not clear is the main symptom of ischemia LA of vertigo. The main symptom factors are Phlegm and Stagnation of blood. The therapy of reducing phlegm, invigorating the blood and removing stasis is efficacious.