Cirrhosis is a diffuse fibrosis of liver tissue, false lobules and regenerative nodules formed is characterized by chronic liver disease. Liver dysfunction and portal hypertension are the main performance. Multiple system involvement in the clinical decompensated often appearascites, upper gastrointestinal bleeding, hepatic encephalopathy, secondary infection and other serious complications. Cirrhosis is a common disease in China and it is one of the causes of death. Cirrhosis of the liver mainly caused by viral hepatitis. Early diagnosis and timely treatment can significantly improve patients’ survival and the quality of life. The topics to liver cirrhosis as the object of study with the pulse instrument acquisition pulse and pulse graph advantage of the traditional pulse diagnosis, avoid its vulnerability subjective factors and to improve the objectivity of pulse diagnosis, discover pulse and pulse graph the significance of cirrhosis caused by hepatitis.ObjectiveBy means of clinical epidemiology, collected101cases of liver cirrhosis pulse, pulse parameters, clinical symptoms, laboratory parameters, explore the characteristics of the pulse distribution and pulse parameters, and analysis of the pulse, the pulse parameters and clinical symptoms, laboratoryRoom indicators, provide a basis for clinical diagnosis and treatment of cirrhosis.Method1.Epidemiological InvestigationAccording to the inclusion and exclusion criteria, screened to meet the diagnostic criteria of cirrhosis cases, the clinical symptoms of liver cirrhosis collection form to collect cases nearly two weeks of clinical symptoms as well as1week laboratory parameters;2.Pulseã€Ppulse Diagram CollectionThe ShangHai DaoSheng DS01-C pulse diagnostic testing information collection system, acquisition time limited to between15:00-17:00, began collecting subjects supine after15minutes.3. The Establishment of the DatabaseThe application of Excel to establish hepatitis cirrhosis pulse, pulse graph, clinical symptoms, laboratory parameters, database, and data entry. Entry of the original pulse is split into a single pulse to0and1,0represents a pulse, on behalf of a pulse, the pulse parameters input value; clinical symptoms to0and1,0for no,1representative; experiment The ventricular index entry value to0and1, with0being normal,1on behalf of the abnormal.4. Data AnalysisApplicate SPSS16.0statistical software distribution, pulse frequency statistics rank sum test to explore the characteristics of the pulse parameters, by logistic regression analysis and bivariate correlation analysis to explore pulse, pulse diagram and clinical symptoms, laboratory indicators.Result101patients with liver cirrhosis, male76cases, female55cases;20to29years old in3cases,30to39years old in17cases,40to49years in36cases,50to59years in31cases,60to65years in12cases,minimum age of26years old and the oldest65years old, average age47.40±0.94years old; activities of89cases,12cases of quiescent; Child-Pugh A level of46cases,,Child-Pugh B levelof36cases, Child-Pugh C level of19cases; decompensated46cases,55cases of decompen sated.1. the Characteristics of Pulse Distribution(1) The overall original pulse to slow Wiry Wiry, the split single pulse Wiry, mainly bradycardia;(2) Cases of men and women are in line with the overall pulse distribution characteristics, taut pulse, slow pulse mainly The Wiry the rate of emergence of female> male;(3) Pulse of30to39-year-old are common virtual clock,40to49-year-old are common Wiry,50to59years and60to65-year-old are common Wiry, slow pulse. Wiry occurrence rate was60to65years old>50to59years>40to49years>30to39years, the emergence of bradycardia was age more than50years old>age less than50years old;(4) Active hepatitis is more common Wiry, bradycardia, quiescent common Wiry. Activity of the slow pulse rate<quiescent;(5) Child-Pugh class A and Class B common Wiry, bradycardia, and Child-Pugh class C common Wiry the virtual pulse, rapid pulse. With the increase of the Child-Pugh classification, buy occurrence rate performance for Class A<B<C;(6) Liver cirrhosis and decompensated common taut pulse, slow pulse. The emergence of the number of pulse rate performance for the loss of the decompensated> decompensated.2. the Characteristics of the Pulse Parameters(1) The overall pulse parameters characteristics in line with fees trillion Fu "Chinese pulse diagnosis" Wiry pulse-like figure features a description;(2) w of male cases<w of female cases, h3/hl and t1/t of male cases <female, reflecting the duration of the high pressure in the aorta of male cases than female cases short vascular wall elasticity than female patients, but the rate of cardiac ejection;(3) h3performance of40to49years<50to59years<60to65years, w value of the performance is age less than50years old<age more than50years old, w/t performance is also age less than50years old<age more than50years old, reflecting increases with age, vascular tone, or peripheral resistance increases, deterioration of arterial elasticity; and over the age of50cases of primary The intraarterial engage teeth learning time is longer than the age of50cases;(4) t5and w/t performance of active hepatitis<quiescent, h3/hl and h4/h1performance of activities of> the stationary phase, reflecting active hepatitis ventricular diastolic time is shorter, the better vascular wall elasticity, peripheral resistance.(5) t5and t performance as Child-Pugh A level an B level> C level, the h4/h1performance class B<A<C grade, reflecting the pulsation period and ventricular relaxation time for the longest Child-Pugh A, B-class, followed by C-level the shortest peripheral resistance performance for the C-class is higher than the other two.(6) t5, t manifestations of decompensated cirrhosis<decompensated at h4/h1performance for decompensated> decompensated reflect decompensated ventricular diastolic time, shorter pulsation cycle, peripheral resistance.3.Correlation of Clinical Symptoms and Pulse with the Pulse Parameters(1) the Correlation of Pulse and Clinical SymptomsWiry cases are more prone to flank pain, sleep disorders; bradycardia cases are more prone to nausea, abdominal pain and diarrhea before dawn; deep pulse cases are more prone to night sweats, inflation threat, nausea, poor appetite and mouth bitter; the slow pulse cases easier to Yaoxisuanruan, waist cold, sticky stool; the imaginary clock cases more prone to sleep disorders, end grain, loose stools; floating pulse cases more prone to end grain is not; rapid pulse cases more prone to pee reduced.(2) the Correlation of Pulse Parameters and the Clinical Symptomsh4value increased cases more prone to inflation threat, the cases of H5value increase more prone to loose stools4. the Correlation of Clinical Symptoms and Pulse with the Laboratory Parameters(1) the Correlation of Pulse and the Laboratory ParametersNumber of clock cases are more prone to red blood cells abnormal red blood cell hematocrit abnormalities, abnormal serum sodium.(1) the Correlation of Pulse Parameters and the Laboratory ParametersAs ad abnormal lymphocytes are positively correlated; t5and prothrombin time there is a negative correlation between; h4/h1and prealbumin abnormalities, abnormal low-density lipoprotein positively correlated with The total bile acid abnormalities negative correlation; there is a negative correlation between creatinine and w.Conelusion1.More common in patients with cirrhosis Wiry, bradycardia, the pulse parameters Wiry class sphygmogram features.2. Female cases Wiry rate, duration of high pressure in the aorta than men; the male cases elasticity of blood vessels, ventricular ejection rate, myocardial contractile function better than women.3.Age, the increase in the rate of occurrence of the string-like pulse, slow pulse, the elasticity of blood vessels, increased peripheral resistance.4. Active hepatitis, diastolic time shortened, the elasticity of blood vessels and peripheral vascular resistance increases.5.Child-Pugh A to B level, C level development or decompensated decompensated development prompted exacerbations, rapid pulse occurrence rate increased by ventricular diastolic pulsation period becomes longer, increased peripheral resistance.6.Deep pulse, slow pulse, retarded pulse, rapid pulse, virtual clock, floating pulse and parameters H4, h5and liver-related symptoms, stomach-related symptoms, kidney-related symptoms there is a certain relationship, can as risk factors for liver, spleen and kidney three dirty clinical symptoms of liver cirrhosis.7. Rapid pulse and h4/hl, t5, w, as ad can be used as some blood indicators, coagulation parameters, liver function, abnormal lipid levels risk factors. |