Maternal-fetal ABO blood group incompatibility is a phrator immunologicaldisease of blood group of fetal or neonatal hemolytic disease caused by blood groupincompatibility between maternal and fetal.As a result of fetal red blood cells red cells carry antigens from the father, sowhen the fetal red blood cells get into the maternal blood circulation, they stimulatethe mother’s immune system to produce antibodies, the antibodies get into fetal bloodcirculation system through the placenta, then they combine with and do harm to thefetal red blood cells, lead to fetal and neonatal hemolytic. The disease can causeabortion, stillbirth, hydrops fetal, early onset neonatal jaundice, hemolytic anemia,kernicterus and neonatal death. Part of the survivors’ intelligence development canalso be influenced. The common types of the disease include Rh blood groupincompatibility and ABO blood group incompatibility, in our country it mainly performsfor the ABO blood group incompatibility, about96%of hemolytic disease of thenewborn owing to it.In recent years, the disease has caused maternal and obstetric doctors’attention gradually. Its onset is occult, pregnant women also perform without obviousclinical symptoms during pregnancy; the test of serum antibody can diagnose thedisease. It is crucial that to diagnose and treat the disease early. The key of treatingthis disease is the prevention of neonatal hemolysis. Western medicine treatmentduring the pregnancy mainly includes suppression of the immune response betweenmother and son, preventing the fetal hemolysis, timely termination of pregnancy;Neonatal treatment includes to prevent hemolytic disease from happening, to preventnuclear jaundice and the further development of the disease, and to correct theanemia.The name of this disease doesn’t appear in Chinese medicine, the clinicalmanifestation mostly belongs to "damp heat" and "damp". Traditional Chinese medicine has remarkable effect in the early prevention and treatment of this disease.The main method to treat this disease in Chinese medicine is "clearing heat andpromoting diuresis","detoxification and removing blood stasis","nourishing tocolysis".My tutor, Professor Wang Cuixia, who is a director of Obstetrics and gynecologydoctors of Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,engaged herself in medical, teaching, scientific research for more than10years; shenot only focuses on the principle-method-recipe-medicines of traditional Chinesemedicine, but also lay stress on the combination of syndrome differentiation anddisease differentiation. She thinks that the occurrence of the disease mainly related tothe insufficiency of the spleen of the pregnant woman,"damp heat" and "damp" causestasis of blood and Qi, babies are lacking of nutrition, toxin are produced inside. Shethinks that the treatment of this disease in pregnancy is particularly important. My tutorcreated the "Clearing heat and removing dampness Antai recipe" herself to treatMaternal-fetal ABO blood group incompatibility during pregnancy, treated based onsyndrome differentiation, considered the addition and subtraction, has achieved verygood effects. |