Analysis Of The Clinical Features Of Ischemic Hepatitis

Objective: To investigate the clinical characteristics of ischemic hepatitisand acute hepatitis B virus compared with biochemical markers, improve thediagnosis of ischemic hepatitis, reducing its rate of misdiagnosis.Methods: A retrospective analysis of ischemic collected hospital data, FirstAffiliated Hospital of Guangxi Medical University IH58cases in January2013-2014and32patients with acute hepatitis B during the2010-2012period,including sex, age, duration of hospitalization, pre-hospital basis of systemicdisease, the onset of clinical manifestations, complications of late, treatment,prognosis, and laboratory parameters during hospitalization. Analyzed usingstatistical methods and clinical features IH acute hepatitis B were compared.Hepatitis occurs mainly in the elderly over45years of age group; hypovolemicshock, heart failure, respiratory failure and septic shock is a major cause ofmorbidity; characterized mainly after the onset of serum transaminases speed updownhill; ischemia hepatitis higher mortality; hypotension, little or no urine,altered consciousness three indicators are independent risk factors for ischemichepatitis prognosis.Results: Age range of58cases of ischemic hepatitis is1-83years, meanage (48.19±22.74) years, age45years or older in38cases, accounting for65.51%.44males and14females (M: F=3.1:1). In addition to the clinicalmanifestations of ischemic symptoms of hepatitis and jaundice, hepatomegalysigns of loss of appetite, nausea, vomiting, fatigue, etc., are also accompanied bylow blood pressure, difficulty breathing, changes in consciousness, little or nourine, edema, jugular vein filling, etc. performance; multiples of the highestvalue the relationship with the indicators of liver function for the upper limit ofnormal: alanine aminotransferase (ALT):170times, aspartate aminotransferase(AST):441times, bilirubin (TBIL):10.5times, alkaline phosphatase (ALP):13times glutamyl endopeptidase (GGT):14.5, lactate dehydrogenase (LDH):86times. Differences in mortality in patients with non-ischemic hepatitis MODSgroup with multiple organ dysfunction (MODS) was statistically significant ((P<0.05). Would ischemic hepatitis and acute hepatitis B liver function comparison between TBIL, serum albumin (ALB), serum cholinesterase (CHE),the difference was statistically significant ALP (P <0.05).Conclusion: Ischemic hepatitis occurs mainly in the elderly over44yearsold group; characterized mainly after the onset of serum transaminases speed updownhill; higher mortality rates for ischemic hepatitis; hypotension, alteredconsciousness two indicators is independent risk factors for ischemic hepatitisprognosis. In the absence of clinical pathologic examination, may be initiallybased on TBIL, ALB, CHE, ALP and other indicators help identify ischemichepatitis and acute hepatitis B.