An Infant Infected By Leishmania Donovani With Hemophagocytic Syndrome:a Case Report

Objectives:Through a case infected by leishmania donovani with hemophagocytic syndrome, to understand the clinical and epidemiological characteristics of Visceral Leishmaniasis (Kala-azar) during the infant and child, reasonably prevent and treat the infants and children’s Visceral Leishmaniasis.Methods:Collect the data of a child infected by leishmania donovani with hemophagocytic syndrome,retrive the literature, Combining with the case inductive and explain the results reasonably.Results:The child was diagnosed as hemophagocytic syndrome in the non-epidemic region,and was given of the immune inhibitors and support treatment without control of the primary infection. After the transfer,the case was diagonosised as hemophagocytic syndrome secondary to Visceral Leishmaniasis ultimately.But the child,s condtion deteriorated, multiple organ was damaged.The whole course lasted for2months, eventually the child died of bleeding complications.Conclusion:Kala-azar and hemophagocytic syndrome have overlapping clinical features. Children with serious Visceral Leishmaniasis can be secondary to hemophagocytic syndrome, such cases should be given timely treatment of primary infection. Unless the condition is critical, We can stop using the immune inhibitors. IVIG may have some efforts as an adjunct in severe case.If delayed,they will die in a short time.