840Cases Of Non-small Cell Lung Cancer Surgery Treatment Prognosis Analysis

Objective: To analyse the non-small cell lung cancer surgery clinicalcharacteristics, discuss the various of factors related to prognosis, in order toregulate the treatment of non-small cell lung cancer and improve its long-termcurative effect. Methods: In our hospital from January2002to August2013,840cases of surgical treatment of non-small cell lung cancer patients wereretrospectively clinical analysis, according to the new TNM staging methodredefine installment. The various clinical characteristics multi-factor analysisabout the840patients by using the SPSS16.0software package，the survivalcurve estimation according to Kaplan Meier-method, single factor significancetest according to the Log-rank method, multi-factor survival analysis accordingto the COX proportional hazards regression model. Results: The840cases ofpatients with surgically resected non-small cell lung cancer, the median survivaltime is40months,1-year,3-years,5-years survival rates are87.4%、52.8%、36.3%. Single factor analysis shows that the age, gender, smoking, generalclassification, pathology classification, tumor size, lung cancer staging (TNMstaging), the number of cleaning the lymph nodes in the group, the number ofcleaning the lymph nodes, the number of metastasis of lymph node in the group,the number of metastasis of lymph nodes, bronchial cut edge have or have not residual cancer cells, with and without invading nearby important organs;Multi-factor analysis showed that age, gross type, pathological type, tumor size,number of sets of lung cancer staging, cleaning of lymph node, metastasis oflymph node number of the independent factors influencing the prognosis ofpatients. Conclusion:(1)The number of lymph node metastasis wereindependent factors affecting prognosis, with the increase in the number of thenumber of transfer, the patient’s survival rate is reduced, and poor prognosis.The lymph node were in the lower lobe of lung cancer should focus on cleaningfor group7lymph nodes; The left upper lobe and the upper lobe lung cancershould be carried out on the set of lymph nodes,5respectively on cleaning.(2)The new auxiliary combined with postoperative adjuvant chemotherapyshould choose those locally advanced and effective chemotherapy to patientswith operation indications. I~Ⅱ a period should not line of postoperativeadjuvant chemotherapy patients, Ⅱ b~Ⅳ period patients should line ofpostoperative adjuvant chemotherapy.(3) The thoracoscope and conventionalthoracotomy for had no effect on the prognosis of patients.