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Correlation Between Olfactory Disorder And Patients’CT Lund-Mackay Score In Chronic Rhino Sinusitis And Nasal Polyps

Posted on:2015-02-07Degree:MasterType:Thesis
Country:ChinaCandidate:Q F SongFull Text:PDF
GTID:2254330431452449Subject:Otorhinolaryngology
Abstract/Summary:PDF Full Text Request
Objective:Study of information through the olfactory function, sinus CT imaging for patients, analysis of the relationship between the olfactory dysfunction and CT scan in patients with different types of the Lund-Mackay score, provides certain help for the clinical treatment and prognosis.Methods:The T&T olfactory testing method respectively in113cases (226sides), male75cases, female38cases, including70cases of patients with nasal polyps (13cases with two or multiple operation history),43cases of patients with chronic rhinosinusitis. Preoperative olfactory function tests, Lund-Mackay CT score, allergen test (skin prick tests), thenasal polyps were treated with pathological cytology typing.Results:(1)According to the olfactory test results and sinus CT score, application SPSS statistical software for analysis for olfactory function and CT score. Pearson test.(2) All patients with their226nasal sides, correlation analysis of their olfactory dysfunction and Lund-Mackay CT score:r=0579, P<001, the difference was statistically significant.(3)Analysis140sides in patients with nasal polyps, correlation analysis olfactory disorders and Lund-Mackay CT score:r=0.540, P=0.000<001, the difference was statistically significant.(4) Analysis62nasal sides inchronic rhino sinusitis, correlation analysis olfactory disorders and Lund-Mackay CT score:r=0.271, P=0.091>0.05, the difference was not statistically significant.(5)In113patients,46patients had different degrees of olfactory dysfunction, accounted for40.7%. Among the43cases of chronic sinusitis patients, there were9patients with olfactory dysfunction, accounted for20.9%.70cases of patients with nasal polyps in52.9%patients (37cases) had olfactory dysfunction.16cases of the two operation patients,there were10casesof olfactory disorder, accounted for62.5%.(6)70cases of nasal polyps in patients with the pathological examination ofcytological type:plasmocytes12cases, lymphocytes3cases, eosnophils10cases, plasmocytes and lymphocytes18cases, plasma cells and eosnophils17cases,plasma cells and neutrophils7cases, neutrophils3cases. In70cases of nasal polyps, had10patients were detected positive allergen.Conclusions:(1)The degree of nasal polypsin patients with olfactory disorderassociatedwith Lund-Mackay CT scoreswere positive, CT scores in patients with normal olfactory smaller values, the greater the proportion of CT score, the higher the value, the more severe olfactory dysfunction. But Lund-Mackay CT scoring system has some limitations, without considering the olfactory cleft congestion conditions.(2)Patients with chronic rhinosinusitis (without nasal polyps) of the degree of olfactory disorders has nocorrelation with Lund-Mackay CT scores, this research result has certain difference with others.(3)In patients with chronic sinusitis and nasal polyps in20.9%of patients with chronic sinusitis have varying degrees of olfactory dysfunction,nasal polyps patients with olfactory dysfunction in52.9%, multiple operation patients with olfactory dysfunction in62.5%, and the emergence of the phenomenon of the polarization, the olfactory dysfunction to severe and completely lost.(4)lymphocytes, plasma cells and eosinophils were more than other cellsin nasal polyps. Olfactory disorders and nasal polyps may be related to cytological type. There may be related olfactory disorders and hypertension.
Keywords/Search Tags:Olfactory disorders, CT Lund-Mackay score, chronicrhino sinusitis, nasal polyps
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