Vitamin D Nutrition Status In Newborns

Objective To know the nutritional status of the newborns in Lanzhou city by measuring serum25-hydroxyvitamin D[25(OH)D].parathyroid hormone(PTH). Calcium and Phosphorus concentration,and to give some potentially useful data for the clinical practice of vitamin D supplementation.Methods90subjects hospitaled newborns within10days after birth were recruited during2012/09-2012/12in First Affiliated Hospital of Medical College in Lanzhou University,and quantitatively determine the serum25(OH)D. PTH levels of the blood samples with ELWASA method. According to gestational age,newborns were divided into two groups:preterm group was30cases, Full-term group were60cases. Using uniform questionnaire.The correlation of25(OH)D with PTH was evaluated. Calcium and Phosphorus concentration was measured by Beckman AU2700automatic biochemical analyzer.Results The adequate proportion of serum25(OH) D in newborns was5.6%, insufficiency proportion was13.3%, deficiency proportion was81.1%,there was no serious deficiency proportion.The serum concentration of25(OH)D in premature infants (21.9±2.5) nmol/L was significantly lower than full-term infants (34.9±10.8)nmol/L (P<0.05).The serum concentration of PTH in premature infants(94.7±40.2)pg/mL was significantly higher than full-term infants(56.1±30.0)pg/mL (P<0.05).There were negative relationships between two cases(P<0.05). The serum concentration of Calcium in premature infants (2.1±0.3) mmol/L was lower than full-term infants(2.3±0.3) mmol/L (P<0.05). The serum concentration of Phosphorus between two cases have no relationships (P>0.05)Conclusions The vitamin D nutritional status of newborns in Lanzhon is not optimistic,we should supervise vitamin D nutrition of the newborns, pregnancy women and breast feeding women.