The Epidemiological Investigation And Risk Factors Analysis Of The Osteoporosis In Elder Men In Changchun Urban Area

The purpose of this study is to investigate the basic situation of bonemineral density and analyze the risk factors of osteoporosis in elderly men inChangchun, aim to prevent and treat the disease.Long-term male residents aged40and above in Changchun, are recruited tocalculate the prevalence of osteoporosis and osteopenia (2344people in total,ranged from40to86years old). The participants were divided into two groups,according to bone density test results: bone density reduced group (797people,including osteoporosis and osteopenia patients) and control group (1547people).Sahara quantitative ultrasonography was used to measure calcaneal bonemineral density. Prevalence of osteoporosis and osteopenia for wholeparticipants were analyzed, and analyze the association between age and OPprevalence. The effects of education, body mass index (BMI), waistcircumference, blood glucose and lipid, blood pressure, as well as dietary habitson the bone density reduction were investigated. A multivariate logisticregression was used to find out risk factor of OR and confidence interval.Results:1) In survey population, the prevalence of osteoporosis andosteopenia were3.3%and30.7%, respectively. The prevalence of osteoporosisand osteopenia were increased with aging.2) Univariate analysis showed thatbone density reduced group with elder age, lower body weight, BMI, and ALTcompared that in control group, the difference has statistically significant(p<0.05). After stratification for BMI, the prevalence of bone density reductionwas decreased obviously with increased BMI. As for smoking, the prevalence ofbone density reduction among non-smokers was significantly lower than thatamong ex-smokers and smokers. For the sports, people with regular physicalexercise have a lower prevalence of bone density reduction than those peoplewithout exercise regularly (p<0.001).3) Multivariate logistic regression analyses showed that age (OR=1.538, p=0.03) and smoking (OR=1.401, p=0.007)were independent risk factors of bone density reduction, while regular exercise(OR=-0.341, p <0.001) was a protective factor.Conclusion: middle-aged males should be wary of osteoporosis with ageincreasing. Smoking cessation and regular exercise could protect bone mass andreduce the incidence of osteoporosis.