Analysis Of Risk Factors And Coronary Artery Angiographic Characteristics Of Sexual Difference In Patients With Acute Coronary Syndrome

Purpose:In recent years, the controllable risk factors in patients with acute coronarysyndromes have been widely studied,but for the epidemiological characteristicsresearch of uncontrollable factors such as sexual differences is less. This articlecompared risk factors with coronary artery angiographic characteristics of sexualdifference in patients with acute coronary syndrome, providing the basis for clinicaltreatment of patients with ACS.Methods:Consecutive cases of hospitalized patients with ACS were collected at Hospitalof Jilin University during August2012to November2013. Diagnosis upon dischargeincludes unstable angina, acute non ST-elevation myocardial infarction and acutemyocardial infarction. All patients accepted coronary angiography. Unstable anginaand non ST segment elevation myocardial infarction were confirmed by Chineseguidelines (Chinese Medical Cardiology Subcommittee, Chinese Editorial Committeeof Cardiology Journal,2012). Acute ST segment elevation myocardial infarctionwere confirmed by Chinese guidelines (Chinese Medical Cardiology Subcommittee,Chinese Editorial Committee of Cardiology Journal,2010).Decision criteria ofcoronary artery angiographic characteristics: coronary artery stenosis50%or leftmain coronary artery stenosis40%is defined as a positive. LM,LAD,LCX,RCA isdefined as the main coronary artery.325patients with acute coronary syndrome (ACS)were divided into male group (211patients) and female group (114patients). Data ofpatients with ACS within the premature group(178patients) and the elderly group (57patients) about their risk factors，coronary artery angiographic characteristics havebeen analyzed.The risk factors of ACS and the features of coronary lesions wereillustrated. Retrospective study was utilized. We recorded the demography information and in-hospital treatments for these patients. The impacts of gender, age,blood sugar, the duration of hypertension, blood lipids (TC, TG, LDL-C, HDL-C),smoking rate, family history of coronary heart disease were assessed. Date analysiswere performed using the SPSS16.0software.Results:1. Compared with male with acute coronary syndrome patients,female with acutecoronary syndrome patients had significantly higher smoking rate (50.8%vs19.9%,p<0.01) and family history of coronary heart disease (19.2vs9.47, p<0.01).2. Compared with female acute coronary syndrome patients,male acute coronarysyndrome patients had more LAD single vessel lesion (p<0.05). Compared withfemale premature acute coronary syndrome patients,male premature acute coronarysyndrome patients had more LAD single vessel lesion.3. Compared with male premature acute coronary syndrome patients,femalepremature acute coronary syndrome patients had significantly higher smoking rate(47.4%vs17.6%, p<0.01),hypertension(46.7%vs28.4%, p<0.01) diabetesmellitus(25.3%vs14.6%, p<0.05),family history of coronary heart disease (11.4vs3.05, p<0.05).4. Compared with elder acute coronary syndrome patients, premature acutecoronary syndrome patients had significantly higher smoking rate,family history ofcoronary heart disease and more male patients(p<0.05).Conclusion:1.female group in patients with acute coronary syndrome (ACS) are more relevantto coronary risk factors such as smoking, family history of coronary heart disease.2. female group in patients with premature acute coronary syndrome (ACS) aremore relevant to coronary risk factors such as hypertension, diabetes, smoking, familyhistory of coronary heart disease.3. Single LAD lesion easily affecte in male group in patients with premature acutecoronary syndrome. While other coronary vascular single lesion (LM, LCX, RCA),the double branch lesion and multivessel disease have no significant sexualdifferences.