| Metabolic syndrome (MS) is a clinical syndrome characterized with a complex metabolic disorder. It is composed of diabetes mellirus(DM), fat obesity, insulin resistence, hypertension, high triglycerides and other abnormalities. It is a common disease both in developed and developing countries. Epidemiological study shows it is an important cause and risk factor for various cardiovascular diseases. MS is highly prevalent in the male patients on coronary angiography. So we select this crowd to carry out an epidemiological investigation of MS to study its prevelance, risk factors and cardiovascular complications for the prevention and control of this disease in the community.OBJECTIVETo describe distribution of metabolic syndrome of patients on coronary angiography in the department of cardiology and the department of interventional therapy and to analysis the value of the MS and cardiovascular dangerous factor. This research is to discuss the relationship between common risk factor of MS and characteristics of injured coronary artery for prevention and treatment of coronary heart disease.METHODSBy retrospective cause analysis, We studied 204 cases admitted in the department of cardiology and the department of interventional therapy and operated on coronary angiography from 2002 to 2005. The study collected the BMI, blood pressure, glucose blood sugar, blood fat and other indexes. Coronary stenosis≥50% enrolled in coronary atery disease group. No stenosis or stenosis<50% in control group. According to the luminar diameter of coronary artery. 50%-75%, 76%-90%, 91%-100% were defined as low-grade, middle-grade, high-grade stenosis respectively. According to the number of suffered coronary artery. Single branch, double branches and several branches were defined. Chi-square test was used to compare the prevalence rates; t-test were used to the differences of numerical variables. The independent risk factors were analyzed by using logistic regression analysis.RESULTS1,The prevalence and the composition to distribute of MS: This research totally investigated 204 cases, according to the diagnosis standard, 48% of the studied group had metabolic syndrome. The age-specific prevalence of hypertension, obesity, diabetes mellitus (DM), high triglycerides and low-chonesterol and MS was 52.3%, 35.2%, 36.4%, 55.7%, 37.5% in men age 35 to 54 years, and 56.9%, 62.1%, 50.9%, 67.2%, 56% in men whose age more than 55 years old. Among combinations of five clinical compositions, the three compositions was the commonest. And the three combination, four combination, five combination was 56.1%, 33.7% and 10.2%.2,Risk factors of metabolic syndrome: The result from correlation analysis indicated that the MS was related with smoking, Coronary heart disease (CHD) history in family, DM history in family and other risk factors of combinations of metabolic syndrome. Among those factors, FPG,SBP,TG and BMI enter the logistic equation by statistic significance (P<0.01). OR value of FBP was 3.183. OR value of SBP was 1.077, OR value of TG was 4.787, OR value of BMI was 1.692.3,There was a higher prevalence of MS (53.6% vs 31.4%) in CHD than in non-CHD. Patients. MS, BMI and HDL-C were major risk factors for coronary artery disease. OR value of MS was 2.384, OR value of BMI was 3.689, OR value of HDL-C was 3.219. Single branch, low-grade stenosis in patients who have MS is lower than who have non-MS.CONCLUSIONS The results indicated that metabolic syndrome is highly prevalent in male patients on coronary angiography. FPG,SBP,TG and BMI were major risk factors of metabolic syndrome. MS can accelerate the occurrence and development of CHD. Patients with MS complicated by CHD would have serious and complex coronary lesions. Deepening our understanding and interference of MS is an important pathway of prevention and treatment of coronary heart disease.
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