| Purpose:Through clinical research, the siege menopausal women syndrome serum5-HT, hormones, hormone-related permits, while Remifemin by summarizing the clinical efficacy of5-HT levels in serum concept Chalifumin perimenopausal women syndrome the impact of changes in various syndromes and integral elements before and after treatment in order to investigate the mechanism and scope Remifemin thus for the clinical treatment of the disease and provide an effective and safe method.Method:1.An object of study:According to the "syndrome differentiation School"(2008version), and symptoms of a threshold method to determine the elements of the integral elements of differentiation syndrome and various weights, choose met the inclusion criteria of59cases of perimenopausal women syndrome; which take. Remifemin intervention were23and36who did not intervene.2.Methods:perimenopausal women collected four diagnostic information and blood syndrome, analysis5-hydroxytryptamine (5-HT) and follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), certified hormone the relationship between; experimental group in Remifemin (produced in Germany in summer Bodhisattva natural medicine pharmaceutical company)12weeks, comparing before and after analysis of the evidence of hormone therapy major points, FSH, LH, E2,5-HT’s.Results:1.Permit the distribution of women’s studies prime part of perimenopausal syndrome, in which the disease is located in the liver, kidney, mind mainly to yin deficiency, blood-based, evidence to Yang Kang, qi stagnation, wet, hot main.2.women5-HT research part of perimenopausal syndrome, relationship FSH, LH, E2, between symptom factors:5-HT and FSH were low negative correlation (P<0.05,|correlation coefficient|<0.4), showed a moderate positive correlation with E2(P<0.05,0.4<|correlation coefficient|<0.7);5-HT and LH no correlation (P>0.05); no between5-HT syndrome elements with the correlation (P>0.05); FSH and kidney, liver, mind, yin deficiency, blood deficiency, qi stagnation, Yang Kang, wet, blood stasis correlated (P<0.05), and liver, mind, qi, blood, Yang Kang, stasis was low positive correlation (|correlation coefficient|<0.4), and kidney yin deficiency, qi stagnation, wet showed moderate positive correlation (0.4≤correlation coefficient|<0.7), and spleen, Yang hot no correlation (P>0.05); LH and kidney, mind, yin deficiency, blood deficiency, qi stagnation, Yang Kang, wet, blood stasis correlated (P<0.05), and kidney, mind, blood, qi stagnation, Yang Kang, stasis was low positive correlation (|correlation coefficient|<0.4), and Yin, wet showed moderate positive correlation (0.4<|correlation coefficient|<0.7), and the liver, spleen, Qi, Yang, heat was no correlation (P>0.05); E2with the syndrome elements were not correlated (P>0.05).3.The presence of the experimental group before and after the intervention differences in5-HT levels, but the difference was not statistically significant (P>0.05); before and after intervention FSH, LH, E2was no significant difference (P>0.05); before and after intervention kidney, liver, spleen, mind, deficiency, qi deficiency, blood deficiency, qi stagnation, Yang Kang, wet, hot points difference was statistically significant (P<0.05); before and after intervention yang, stasis points no significant difference (P>0.05); and permit better known for liver, mind, Yin, wet, hot, Yang Kang-based effect.Conclusion:Perimenopausal women syndrome syndrome elements distributed mainly in the liver, kidney, mind, yin deficiency, blood deficiency, Yang Kang, qi stagnation, wet, hot and so on. After Remifemin intervention, kidney, liver, spleen, mind, deficiency, qi deficiency, blood deficiency, qi stagnation, Yang Kang, humidity, heat and other elements integral permit decreased in the liver, mind, Yin, wet, hot, Yang Kang decreased significantly, help guide women of perimenopausal syndrome clinical treatment and prognosis; change after the intervention of serum levels of5-HT was not statistically significant. |
PDF Full Text Request