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The Research Progress Of Cervical Cancer Adjuvant Radiation And Chemotherapy Postoperatively

Posted on:2015-03-24Degree:MasterType:Thesis
Country:ChinaCandidate:X YangFull Text:PDF
GTID:2254330425995166Subject:Clinical medicine
Abstract/Summary:PDF Full Text Request
Cervical cancer is one of the most common malignant tumor in femalereproductive system, about500000new cases each year, accounting for5%of all newcancer cases and80%of the cases from developing countries. China’s cervical cancerpatients reached131500, accounting for28.8%of the world’s new cases of cervicalcancer. And the world each year about200000people die of cervical cancer,accounting for9%of all malignant tumor death toll. Chinese patients with cervicalcancer mortality rate of4.32/100000. As the general investigation are developingextensively in recent years, the improvement of early diagnostic technique,and thepublic to the growth of awareness of cervical cancer, allowing more of the cervicalcancer patients are offered the opportunity to surgery. How to reduce the recurrenceand metastasis of cervical cancer and improve the survival rate is becoming a researchhotspot. This review by consulting a large number of domestic and foreign literature:understanding the present research situation and the progress of cervical canceradjuvant radiation and chemotherapy after surgery; understanding of cervical canceradjuvant radiation and chemotherapy after indications; understanding of cervicalcancer adjuvant radiation and chemotherapy in postoperative method, curative effectand limitation. Choose the database of PubMed, a database of ten thousand, ChineseJournal Full-text Database and Chinese biomedical literature database, Chinaexcellent master’s and doctoral dissertations full-text database and Chinese importantdissertations full-text database, Baidu library and Google academic search, etc.Postoperative radiotherapy as a traditional treatment method to reduce postoperativelocal recurrence rates has certain effect, but the control of distant metastasis is notideal; Postoperative chemoradiation can control the pelvic recurrence and distantmetastasis, improve the survival rate, but its hematology toxicity is obviously, thespecial attention and timely treatment is necessary;There are no unified standards withpostoperative adjuvant chemoradiation at home and abroad, especially the order ofradiotherapy and chemotherapy, the best chemotherapy regimens,the methods anddose of postoperative radiotherapy are all different, remains to be perfected in further;With more attention is paid to the postoperative adjuvant chemotherapy, some research have showed its effect, but postoperative adjuvant chemotherapy can replaceradiotherapy still need further research.
Keywords/Search Tags:cervical cancer surgery, concurrent chemoradiotherapy, radiationtherapy, chemotherapy
PDF Full Text Request
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