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Double Red Huazhuo Party On Experimental Atherosclerosis In Rabbits Blood Lipids And Inflammatory Factors

Posted on:2014-05-28Degree:MasterType:Thesis
Country:ChinaCandidate:M GaoFull Text:PDF
GTID:2254330425967108Subject:Traditional Chinese Internal Medicine
Abstract/Summary:PDF Full Text Request
Objective: by double red Huazhuo party in the role of experimentalatherosclerosis White Rabbit study on the mechanism of action of itsanti-atherosclerosis, laying the groundwork for further study ofanti-AS.Methods:40rabbits, according to body weight were randomly dividedinto normal group, model group, double red Huazhuo party high andlow dose group, western medicine group; modeling administered10weeks. Automatic blood biochemical analyzer lipids, ELISAenzyme-linked immunosorbent assay was used to detect serumhigh-sensitivity C-reactive protein (CRP), tumor necrosisfactor-alpha (TNF-alpha), NF-kB indicators; HE staining, microscopyaortic wall plaque morphology.Results: the double red Huazhuo party TC, TG, HDL-C, LDL-Csignificantly reduced role; significantly reduced C-reactiveprotein, TNF-alpha, NF-kB content; inhibit atherosclerotic plaqueeffect.Conclusion: double red Huazhuo party atherosclerosis hardening hasgood resistance to atherosclerosis hardening and anti-inflammatoryrole in the inflammatory mechanism and further anti-arteryatherosclerosis remains to be further observational studies.
Keywords/Search Tags:atherosclerosis hardening, double red Huazhuo party, Chest Pain, CRP, TNF-a, NF-KB
PDF Full Text Request
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