Objective: by double red Huazhuo party in the role of experimentalatherosclerosis White Rabbit study on the mechanism of action of itsanti-atherosclerosis, laying the groundwork for further study ofanti-AS.Methods:40rabbits, according to body weight were randomly dividedinto normal group, model group, double red Huazhuo party high andlow dose group, western medicine group; modeling administered10weeks. Automatic blood biochemical analyzer lipids, ELISAenzyme-linked immunosorbent assay was used to detect serumhigh-sensitivity C-reactive protein (CRP), tumor necrosisfactor-alpha (TNF-alpha), NF-kB indicators; HE staining, microscopyaortic wall plaque morphology.Results: the double red Huazhuo party TC, TG, HDL-C, LDL-Csignificantly reduced role; significantly reduced C-reactiveprotein, TNF-alpha, NF-kB content; inhibit atherosclerotic plaqueeffect.Conclusion: double red Huazhuo party atherosclerosis hardening hasgood resistance to atherosclerosis hardening and anti-inflammatoryrole in the inflammatory mechanism and further anti-arteryatherosclerosis remains to be further observational studies. |