Purpose: To comparative effects of discrimination on the pure antiviraltreatment(Baraclude) and joint Soup,Established chronic hepatitis B(stagnation of liver qiand spleen deficiency)treatment programs and efficacy evaluation method.Method:60patients with chronic hepatitis B were randomly divided into test groupof30patients(Sinierjin Soup joint Entecavir)and a control group of30cases(onlyEntecavir),after6months, observe the indicators of the efficacy of TCM clinicalsyndromes, liver function, abdominal ultrasonography, HBV-DNA and safety indicators.Results:The test total effective rate was73.3%, the control group was60%, the totalefficacy test group was better than the control group。However, due to the observation timeis shorter, the difference was not statistically significant (P>0.05). Experimental group wasbetter than the control group in improving the indicators of liver inflammation, immuneindicators, TCM clinical evidence candidate,the difference was statistically significant (P<0.05).After the comparison treatment, the difference was not statistically significant(P>0.05) on improve liver and spleen B hepatitis B seroconversion rate, HBV-DNAnegative conversion aspects.Conclusion:Entecavir antiviral therapy based on the joint the herbal compoundSinierjin Soup can effectively improve the chronic hepatitis B liver inflammation, immuneindicators. And combination therapy was safe and effective, the CHB Integrativestandardized treatment (stagnation of liver qi and spleen deficiency)and research providean objective basis for us,and this has some practical value, and was worthy of promotionin clinical application. |