Metabolism Related Factors And Mild Cognitive Impairment In Aged Of The Chongqing China

Objective: The aim of this study was to found the metabolic factors ofMCI in aged of the Chongqing, China.Methods: Montreal Cognitive Assessment Beijing version (MoCA-BJ)was applied as cognition assessment implement. There were seventycommunities with MCI and one hundred and eighty-seven communitiesnormal controls (NC), eighty-three inpatients with MCI and one hundredand forty-five inpatients NC after the screening. Basic information containsage, gender, education background, whether or not out of work, history ofsmoking, habitual alcohol drinking, history of disease, family history, dataof BMI, WHR, HbA1c, fasting blood glucose (FBG),2hours postprandialblood glucose(2hPBG), uric acid(UA), creatinine(Cre), Total cholesterol(TC), HDL cholesterol (HDL-C), LDL cholesterol (LDL-C) andtriglyceride (TG), high-sensitivity C-reactive protein (HsCRP) wascollected. Results: The MoCA-BJ scores was positively correlated witheducation background but negatively correlated with gender and age. Therewere significant differences in the incidence of CHD, HbA1c, and nosignificant differences in the incidence of COPD, TIA, T2DM, familyhistory of dementia, smoking, out of work, BMI, WHR, FBG,2hPBG, TG,TC, HDL-C, TC/HDL-C, LDL-C, UA, Cre, HsCRP between NC groupand MCI group in inpatients. In communities, there were significantdifferences in the incidence of T2DM, passive smoking, FBG,2hPBG,HbA1c, TC, HDL-C, and no significant differences in the incidence ofCHD, COPD, TIA, T2DM, family history of dementia, out of work, BMI,WHR, TG, TC/HDL-C, LDL-C, UA, Cre, HsCRP between two groups.Conclusions: Our results suggest that history of T2DM, level ofglucose, level of TC could be risk factors of MCI in aged. BMI, WHR, UA,Cre, LDL-C, HsCRP not were associated with MCI.