The Research Of Low Intensity Ultrasound Irradiation For Postpartum Uterine Involution

Clinical survey found that due to the increase in clinical cesareandelivery rate and high-risk pregnancy maternal increases, the weakness ofpostpartum uterine contractions and uterine instauration adverse risk haveobvious rising trend. Uterine smooth muscle contraction is the necessarycondition of uterine instauration, postpartum mostly by drugs to promoteuterine smooth muscle contraction, but all have certain side effects.Therefore, looking for a kind of physical therapy in vitro method topromote postpartum uterine redintegration is imperative.Low intensity ultrasonic physical therapy because of its noninvasive,no side effect, convenient operation and get more and more attention fromthe researchers. Studies show that low intensity ultrasound can promotepregnancy mice, rats in vitro and rats in vivo and people in vitro uterussmooth muscle contraction, and without damage to the organization. Thisexperiment based on the previous studies, the use of low intensityultrasound irradiation people living postpartum uterus, observe its effect onpostpartum uterine redintegration, proposed for application of low intensity ultrasound in promote clinical postpartum uterine redintegration people toprovide powerful basis.Objective1. To observation of the uterus decreased height and the end ofpostpartum lochia after use low-intensity ultrasound treat the uterine-incision delivery patients. Explore the impact of low-intensity ultrasoundirradiation on cesarean section uterine involution.2. To observation of the uterus decreased height and the end ofpostpartum lochia after use low-intensity ultrasound treat the spontaneousdelivery patients. Explore the impact of low-intensity ultrasound irradiationof cis postpartum uterine involution.3. To observation the effect of low intensity ultrasound on ER and cyclinE Expression in Rats’ uterine after abortion induced by medication and toobserve specimens rat uterus and uterine histopathological changes. Discussthe mechanism of treating uterine delivery after abortion.Method1.144patients as research subjects, both after cesarean section wererandomly assigned to two groups,80cases of the treatment group,64casesof the control group, the treatment group patients were treated bylow-intensity ultrasound by30min every half day after delivery24h to thirdday, the control group were according to false. The clinical observation oftwo groups of patients before treatment harem bottom dropped the case, the end of the bloody lochia serous lochia days.2.124patients as research subjects, both after natural birth wererandomly assigned to two groups,63cases of the treatment group,61casesof the control group, the treatment group patients were treated bylow-intensity ultrasound by30min every half day after delivery6h to thirdday, the control group were according to false. The clinical observation oftwo groups of patients before treatment harem bottom dropped the case, theend of the bloody lochia serous lochia days.3.20pregnant SD rats were divided into two groups, and completeabortion models after abortion were made by using Mifepristone andMisoprostolat7th day. Treatment group were treated by low intensityultrasound30min every day after delivery one day to seventh day. Eachgroup of models was killed after7d and then expression of ER and cyclinEwere tested by Immunohistochemistry method and detectedhistopathological change.Result1. Cesarean delivery before ultrasonic treatment group treatment harembottom index was17.26±6.13%, control group is false according to formerimperial harem bottom index was8.92±6.10%, treatment group was betterthan control group (P <0.05); Cesarean delivery end of ultrasound treatmentgroup hemorrhagic lochia days was6.35±2.51days, the control end ofhemorrhagic lochia number was8.17±3.32days, ultrasonic treatment group was significantly earlier than the control group (P <0.05); Cesareandelivery end of ultrasound treatment group hemorrhagic lochia days was30.51±10.98days, the control end of hemorrhagic lochia number was34.63±9.33days, ultrasonic treatment group was significantly earlier than thecontrol group (P <0.05).2. Natural labor ultrasonic treatment group before treatment harembottom index was21.12±5.71%, control group is false according toformer imperial harem bottom index was9.48±4.77%, treatment groupwas better than control group (P <0.05); Natural labor ultrasonic treatmentgroup hemorrhagic lochia end days was6.25±2.45days, the controlhemorrhagic lochia end days was8.74±3.45days, ultrasonic treatmentgroup obviously earlier than the control group (P <0.05); Natural laborultrasonic treatment group hemorrhagic lochia end days was31.83±9.18days, the control hemorrhagic lochia end days was34.84±9.55days,ultrasonic treatment group obviously earlier than the control group (P <0.05).3. By observe gross tissue section and HE staining, uterine instaurationaccelerated than control group in treatment group. The expression oftreatment group of uterus tissue ER and cyclin E was significantly betterthan control group (P <0.05).Conclusion1. Using low intensity ultrasound irradiation after cesarean section in patients with fundus of uterus abdominal area can speed up the uterinefundus decline, reducing hemorrhagic lochia and serous lochia over time,which can effectively promote the instauration of uterus after cesareansection. Using low intensity ultrasound irradiation after natural birth inpatients with fundus of uterus abdominal area can speed up the uterinefundus decline, reducing hemorrhagic lochia and serous lochia over time,can effectively promote the birth to postpartum uterine redintegration.2. Using low-intensity ultrasound irradiation medical abortion the ratuterus abdomen coverage area can speed up the the rat uterine involutionspeed, increasing the rat uterus ER and cyclin E expression.