Clinical Analysis Of130Cases Of Hypertensive Disorders In Pregnancy Maternal

Objective:1. Compare risk of hypertensive disorders in pregnancy pregnant women andnormal pregnant women before delivery and after child birth complications ofpregnancy outcomes, the relationship between perinatal outcome.2. Compare risk of hypertensive disorders in pregnancy pregnant and normalpregnant women before delivery coagulation indicators change.3. Explore the hypertensive disorder complicating pregnancy adverse pregnancyoutcomes and coagulation.Methods:1. Research methods and objectA retrospective analysis of controlled studies, Select the First Affiliated Hospital ofDalian Medical University, obstetrics, Between January2010and December2011inhospital childbirth130cases of maternal gestational hypertension disease as a researchgroup.Including gestational hypertension in14patients (study group1); pre-eclampsia-eclampsia60cases (study group2); chronic hypertension complicated by preeclampsia38patients (group3); pregnant women with chronic hypertension18patients (studygroup4). According to1:1proportion, Randomly selected130cases hospitalizednormotensive pregnant women as a control group for the same period.2. research contentsRecord the general information of the two groups of pregnant women(Age,gestational age, gravidity, parity, past history, family history), Clinical information onbefore childbirth and after childbirth complications and comorbidities, pregnancyoutcome, mode of delivery, perinatal complications of children. Comparison of twogroups of pregnant women blood coagulation correlation indicators, Including some liveclotting time (APTT), prothrombin time (PT), thrombin time (TT), fibrinogen (Fib),platelet count (PLT), average blood platelet volume (MPV) and so on. Result:1.The classification of the study group, constitute the highest ratio forpre-eclampsia-eclampsia; The mean gestational age at the time of delivery of the studygroup than the control group; Familial history of hypertension, the more prone toadverse pregnancy.2.Comparison of pregnancy complications: Study Group project comparison beforedelivery and after delivery in obesity, thyroid disease, blood disorders, heart disease,hepatitis, uterine fibroids and other diseases, the incidence rate higher than that of thecontrol group, the difference was statistically significant (P <0.05); incidence ofpregnancy complications in the study group top three were: obesity, uterine fibroids,thyroid disease.3.Comparison of pregnancy complications: The study group before and afterchildbirth in premature rupture of membranes, gestational diabetes，fetal growthrestriction, the umbilical cord around the neck, HELLP disease project comparison, theincidence rate was higher, the difference was statistically significant (P<0.05); the topthree of the incidence of pregnancy complications in the study group were: gestationaldiabetes， umbilical cord around the neck, fetal growth restriction.4.The comparison of the outcome of pregnancy and childbirth: The study group theincidence of premature delivery and abortion was significantly higher than that in thecontrol group, while the term delivery rate than the control group, choice of deliverymodein the study group the use of cesarean section termination of pregnancy, while thecontrol group the use of vaginal delivery, the difference was statistically significant(P<0.05).5.Comparison of perinatal children:"fetal distress" of the study group and theincidence of premature children is much higher than that of the control group, and thedifference was statistically significant (P <0.05); the Study Group newborns more proneto fetal distress, the control group.6.Comparison of coagulation indicatorsStudy Group2in the APTT, MPV comparison than the control group, the studygroup3"APTT, PT, TT, MPV" comparison than the control group, the study group islower than that of the control group in the TT comparison, these comparisons werestatistically significant (P <0.05). Conclusion:Pregnancy-induced hypertension is a peculiar disease of late pregnancy. Has aserious threat to the life of the mother and child. Good management at different levels ofpregnancy-induced hypertension and clinical symptoms monitoring, to discover andmaster the process of the development of the disease, and to develop effective measuresto reduce the PIH serious complications, and actively improve the prognosis of perinatalchildren, to improve the perinatal child survival is important.Coagulation indicators detected in the prediction of pregnancy-inducedhypertension, because of its less invasive, easy to operate, begin screening earlier,screening a wide range of high sensitivity and specificity, is a better method. Worthy ofclinical application.