Objective methods:To observe the clinical effect and safety by using the method of JianPiHuoXue prescription in treating Chronic Atrophic Gastritis with Spleen deficiency and Blood stasis Syndrome. And observe the long-term curative effect after following up for3months.Research methods:According to the standard scheme, choose the traditional Chinese and Western medicine diagnosis standard of CAG in precancerous lesions of90patients, randomized controlled method, divided into45cases of test group patients,45patients in control group patients. The experimental group was given Jianpi Huoxue Decoction treatment, control group were given Weifuchun tablets,3month is1treatment course, the treatment time was3months,3months follow-up.Research result:1. Comparison of overall treatment efficacy after3months:45cases of test group patients, the clinical cure in12cases, effective in16cases, effective13cases, invalid4cases, the total effective rate was91.11%; the control group45cases of patients,8cases were cured, effective in10cases, effective15cases, invalid12cases, the total efficiency is73.33%. The statistical analysis of P<0.05, there was significant difference in the overall efficacy of the two groups. The test group was better than control group.2. Comparison of3months of gastroscope and biopsy after treatment:Two groups were improved in patients with the severity of dysplasia, and the curative effect is similar, but to improve patients with gastric atrophy, intestinal metaplasia degree, efficacy of the test group was the control group, the curative effect is not obvious, the test group was better than control group.3.3months after discontinuation of follow-up of two groups of clinical curative effect, in45cases of test group of patients,15cases were cured,13cases markedly effective, effective15cases, invalid2cases, the total effective rate was95.56%; in45cases of patients in the control group,8cases were cured,10cases markedly effective, effective in12cases,15cases ineffective, the total effective rate was66.67%. By statistical analysis of P<0.05, the two groups had significant difference, the experimental group is superior to control group.4. In the course of treatment and follow-up, no adverse reaction was foundResearch conclusion: To observe the clinical efficacy of Jianpi Huoxue Decoction "in the treatment of precancerous lesions of CAG syndrome of spleen deficiency and blood stasis, clinical symptoms can not only improve the patients, but also to some extent reverse atrophy, intestinal metaplasia, dysplasia. |