The Study Of Fetal Lateral Ventricle Development Of22-27Weeks By In Vivo Fetal Ultrasound And Postmortem MRI

Objective:To study the law of22weeks to27weeks fetal development of lateral ventricle by Ultrasound and MRI techniques.To set up the reference value of normal fetal ventricle system between the different gestational age,to discuss the influence of gestational age and to provide medical value and the law of development of the lateral ventricle for clinical diagnosis.Methods:A retrospective review of360pregnant women in22weeks to27weeks gestation by ultrasound examination,aged19-41years,were studied during August2001to March2013.The width of lateral ventricle was measured at lateral ventricle plane by the Ultrasound.And then selected16fetal specimens from22weeks to27weeks that due to spontaneous abortion or drug caused abortion for the lesions out of the brain,were scanned by MRI.Measured the lateral ventricle at the axial and coronal MRI images.The postmortem MRI and in vivo fetal Ultrasounds of the same age were analyzed to obtained the development conditions.Results:The width of lateral ventricle of the total group mean measured by in vivo fetal Ultrasound and postmortem MRI were0.60±0.08、 0.59±0.10、0.59±0.09、0.64±0.15、0.64±0.09、0.65±0.08and4.73、5.15、5.03、4.70、4.88、4.8,respectively,and the maximum less than1.0cm.There were good consistencies between the in vivo fetal Ultrasound and postmortem MRI.The size of the lateral ventricle showed no significant relationship between gestational age, There were no correlation between the width and the gestational age in fetuses(P>0.05).Conclusions:The maximum width of the lateral ventricle less than1.0cm in22weeks to27weeks gestation, There is no obviously correlation between the fetal lateral ventricle and gestational age in fetus.