Research Of TCM Syndrome Distribution Regularity Of Acute Phase Of Hemorrhagic Stroke In Different Time Points

Objective: Through clinical observation in patients with acute hemorrhagic stroke, thepatiens’ clinical information including TCM syndrome and imaging information wascollected at different time points, aimed to explore the distribution and evolution of TCMsyndromes in the different periods of the acute phase of cerebral hemorrhage, and thecorrelation between image changes with TCM syndromes. In order to provides the pathologicbasis and objective index for the diagnosis and treatment of acute hemorrhagic stroke.Methods:①According to the “Stroke in quantitative diagnosis of syndromes ratingscale”, we collected165cases of patients’ syndrome in the acute phase of cerebralhemorrhage, the collection points are: the first day of admission,7days,14days and21daysafter admission. Analyzing each syndrome score and the proportion, and the syndromedistribution form in different time points.②Using the National Institutes of Health StrokeScale (NIHSS) to assess the patients’ neurological function. Analyzing the difference ofNIHSS score of each syndrome, and the relationship between NIHSS score and TCMsyndrome score.③Examing the brain CT with patients in forty eight hours to statisticbleeding sites, bleeding volume, the structure of the midline, and the relationship betweensyndromes and the imaging changes. Finally using the SPASS17.0software for statisticalanalysis of data.Results:①After admission the Wind score decreases fastest, then maintain a low level;the Heat score also decreases gradually in the course of disease, but within7days it doesn’tchange significantly,7days later the score begin to decline rapidly; the Phlegm score keep ahigh level in7days after admission, then gradually decreases; the Blood Stasis scoregradually increases after admission, although there is a downturn after14days but it stillmaintaining a high level; deficiency of Qi and deficiency of Yin syndrome scores show littlechange, has been maintained at a relatively low level. About the syndrome distribution, Heatsyndrome has always been in the first place; Wind syndrome lives in the second in the first7days, then drops to fourth at14days and21days; Phlegm syndrome lives in the third at the first day of admission, and living in the fourth at7days, then rising to second place at14days,but at21days it fells to fifth place; Blood Stasis rises gradually from fourth to second;deficiency of Qi syndrome has been in fifth in the acute stage, but has risen to third place at21days; deficiency of Yin syndrome has always been the last one. Acute hemorrhagic strokesyndromes combination is given priority to two card, three card combination. On the first day,the main form of two card combination are Heat+Wind, Heat+Phlegm, and three cardcombination are Heat+Wind+Phlegm and Heat+Phlegm+Blood Stasis;7days later, Heat+Phlegm has been in the first place and Wind+Phlegm in the second of two card combination.The main form of three card combination are Heat+Phlegm+Blood Stasis and Phlegm+Blood Stasis+Wind; On the14days Heat+Phlegm remains in the first place, second only tothe Heat+Blood Stasis. Heat+Phlegm+Blood Stasis, Phlegm+Blood Stasis+deficiency ofQi are the main form of three card combination; Till the21days, deficiency syndrome havebecome increasingly important, the main form of two card combination are Heat+BloodStasis and Heat+deficiency of Qi. Heat+Blood Stasis+deficiency of Qi and Phlegm+BloodStasis+deficiency of Qi rise to the top of three card combination.②Most of the patients, theNIHSS score were significantly decreased after the treatment, but each syndrome’s NIHSSscore showed no difference. Correlation between TCM syndrome score and NIHSS score: Inthe first and fourteenth days, Heat, Phlegm, deficiency of Qi associated with NIHSS score;Wind had good linear correlation with NIHSS score in acute stage of stroke, but thecorrelation had disappeared at14days.③The bleeding sites are mainly in the basal gangliaand thalamus; In the bleeding sites, Wind, Heat and Phlegm syndrome are high; Theincidence of Heat and Phlegm syndrome in massive bleeding group is higher thanmidst-dimin bleeding group; The incidence of Wind, deficiency of Yin in massive bleedinggroup is lower than the midst-dimin bleeding group; The incidence of Heat and Phlegmsyndrome in neutral-line displaced group is higher than neutral-line centre group.