The Burden Of Rhinitis During Pregnancy And The Prenatal Risk Factors Of Eczema In Infancy

Objective: This study Aimed to survey the symptoms of rhinitis and its influence to qualityof life during pregnancy.Methods: A retrospective study of pregnancy awaiting delivery in the department ofobstetrics and gynecology and non-pregnancy (nullipara of bearing age, acting as a controlgroup) selected from medical examination center was conducted by a questionnaire at thehospitals during the same period in wuhan, china. Then rhinitis symptoms and quality oflife were compared between two groups.700pregnancies and783non-pregnancies wereincluded in this study.Result: The prevalence of self-reported rhinitis in pregnancy (19.7%) was significantlyhigher than non-pregnancy (12.1%) at the same time (P=0.000). The scores of severityabout rhinocnesmus, sneezing and rhinorrhea in pregnancy were significantly lower than(P=0.000,0.000,0.000, respectively) non-pregnancy, but not nasal obstruction (P=0.957). Domains scores and total scores for rhinoconjunctivitis quality of life questionnaire (RQLQ)in pregnancy were not significantly higher than non-pregnancy, in addition to domains ofsleeping problems and nasal symptoms. The domain score of sleeping problems inpregnancy was significantly higher than the score in non-pregnancy. The domain score ofnasal problems in pregnancy was significantly lower than the score in non-pregnancy. Theclassifications of IRIA in pregnancy and non-pregnancy were not significantly different.Conclusion: The incidence of rhinitis during pregnancy were apparently higher thannon-pregnancy during the same period, but the scores of rhinitis symptoms were lower thanthe control group. Compared with the control group, the influence of rhinitis symptoms topregnant women’s sleep was more serious. Objective: The present prospective study examined the association between prenatalfactors and the risk of physician diagnosed eczema among infants aged6months.Methods: Subjects were328mother-child pairs. Information on maternal factors duringpregnancy was assessed with a self-administered questionnaire when waiting delivery. Theterm ‘physician diagnosed eczema’ was used to define an outcome based on results of ourquestionnaire completed by telephone interview at6months of age.Results: The prevalence of infantile eczema was45.4%(149/328). Allergic rhinitissymptoms, keeping cat or dog and traffic-related air pollutants during pregnancy weresignificantly associated with increased risk of eczema in the offspring (Adjusted OR:1.82，2.661，2.873, respectively. Adjusted95%CI：1.073-3.086，1.020-6.945，1.059-7.794,respectively).Conclusion: The environment factors and health factors during pregnancy may beimportant potential risk factor regarding to the risk of infantile eczema. We found noevidence that the dietary factors during pregnancy impacted the risk of eczema in infancy.